Results 111 to 120 of about 6,206,849 (362)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Science et sciences sociales

open access: yesBulletin de la Classe des lettres et des sciences morales et politiques, 1986
info:eu-repo/semantics ...
openaire   +3 more sources

Basic concepts in social sciences III [PDF]

open access: yes, 2004
In this paper the set of concepts considered to be basic to the fields of Economics, Organization Theory, Political Science, Psychology and Sociology is completed.
Hoede, C.
core   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

A Methodological Blueprint for Social Sciences Research – The Social Sciences Research Methodology Framework

open access: yesEIRP Proceedings, 2020
Most research practice constructs in social sciences are predominantly well defined and constructed, yet many authors hold different interpretations of certain key terms and concepts, causing a degree of confusion, overlap and uncertainty.
Norbert E Haydam, Pieter Steenkamp
doaj  

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

The innovation bias: Implicit preferences for innovative and historical solutions over contemporary ones

open access: yesiScience
Summary: Innovative products and services promise to improve our lives in many ways. Novel, unfamiliar approaches, however, also come with increased uncertainty regarding their feasibility and quality.
Moritz Reis   +3 more
doaj   +1 more source

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