Results 141 to 150 of about 6,206,849 (362)

Methods matter: Exploring how expectations influence common actions

open access: yesiScience
Summary: Behavior in controlled laboratory studies is not always representative of what people do in daily life. This has prompted a recent shift toward conducting studies in natural settings.
Andrea Ghiani, David Mann, Eli Brenner
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

COVID-19 test-to-stay program for K-12 schools: Opt-in versus opt-out consent model

open access: yesiScience
Summary: The Centers for Disease Control and Prevention promoted the Test-to-Stay (TTS) program to facilitate in-person instruction in K-12 schools during COVID-19.
Anton Ivanov   +8 more
doaj   +1 more source

US publisher moves to make catalogue of over 4,000 academic texts available free online [PDF]

open access: yes, 2011
In a new move to make academic content more accessible to a wider audience across the globe, the National Academies Press announced this month that PDF versions of all its books will be available for download to anyone across the globe free of charge ...
Impact of Social Sciences Blog, at LSE
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Assessing the impact of armed conflict on the progress of achieving 17 sustainable development goals

open access: yesiScience
Summary: With global armed conflicts reaching a 30-year high in 2023, understanding their impact on the progress of Sustainable Development Goals (SDGs) is crucial.
Di Wang   +3 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

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