Results 181 to 190 of about 6,448,019 (366)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Together, No. 11 [PDF]

open access: yes, 2017
San Jose State University, College of Social Sciences
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Conservation and the social sciences revisited. [PDF]

open access: yesConserv Biol
Dietsch AM   +11 more
europepmc   +1 more source

Thermodynamics 2.0: Bridging the natural and social sciences. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci, 2023
Poudel R   +5 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Making social sciences foundational to academic medicine. [PDF]

open access: yesPLoS Med
Sadjadi S   +3 more
europepmc   +1 more source

Survey of open science practices and attitudes in the social sciences. [PDF]

open access: yesNat Commun, 2023
Ferguson J   +8 more
europepmc   +1 more source

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