Results 51 to 60 of about 6,022,409 (321)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

ДОРНО, ӨРНӨДИЙГ ХОЛБОГЧ ГҮҮР, ОНЦ БӨГӨӨД БҮРЭН ЭРХТ ЭЛЧИН САЙД, ИЛ ХАНТ УЛСАД МОНГОЛ “АХ” НЭРЭЭР ДУРСАГДАН ХҮНДЛЭГДСЭН БОЛОД ЧИНСАН

open access: yesProceedings of the Mongolian Academy of Sciences, 2016
Болодын талаар дэлгэрэнгүй тэмдэглэл Монголд өнөөдрийг хүртэл нийтлэгдээгүй бөгөөд би Иран улсад 2015 онд Монголын ШУА-ийн төлөөлөгчдийн бүрэлдэхүүнд оролцохдоо түүнийг мэдэрч судалгааг эхэлсэн юм. Цөөн Монгол эрдэмтэн түүний тухай товчхон бичсэн байдаг.
О Нямдаваа
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

An Error-Correction Model for Information Transmissions of Social Networks [PDF]

open access: yesarXiv, 2023
We study the error-correction problem of the communication between two vertices in a social network. By applying the concepts of coding theory into the Social Network Analysis (SNA), we develop the code social network model, which can offer an efficient way to ensure the correctness of the message transmission within the social netwoks.
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The Allergic Bodies Conference: Postgraduate/Postdoctoral Research Conference, 2010 [PDF]

open access: yes, 2010
This is the programme document for the annual Postgraduate/Postdoctoral Research Conference with Keynotes: Dr Jennifer Bajorek (Goldsmiths), Marianne Sjelsford (National Academy of Arts, Oslo, Sweden); Dr Maarten Vanvolsem (Lieven Gevaert Research ...
Golding, Sue   +2 more
core  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Artificiality in Social Sciences [PDF]

open access: yesRennard, J.-P., Artificiality in Social Sciences, in Rennard, J.-P. (Ed.), Handbook of Research on Nature Inspired Computing for Economics and Management, p.1-15, IGR, 2006, 2007
This text provides with an introduction to the modern approach of artificiality and simulation in social sciences. It presents the relationship between complexity and artificiality, before introducing the field of artificial societies which greatly benefited from the computer power fast increase, gifting social sciences with formalization and ...
arxiv  

Five Minutes with Tim Gowers and Tyler Neylon: “The boycott has made Elsevier more concerned about its public image” [PDF]

open access: yes, 2012
Earlier this year Tim Gowers sparked debate about the future of academic publishing when he declared his intentions to boycott Elsevier. With Tyler Neylon’s work on the Cost of Knowledge website, the pair discuss how they made a splash in the comfy world
Blog Admin, Impact of Social Sciences,   +2 more
core  

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

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