Results 71 to 80 of about 6,071,023 (341)
https://nsuworks.nova.edu/shss_dialogs/1015/thumbnail ...
Graduate School of Humanities & Social Sciences
core +1 more source
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
https://nsuworks.nova.edu/shss_dialogs/1008/thumbnail ...
Graduate School of Humanities & Social Sciences
core +1 more source
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
wiley +1 more source
https://nsuworks.nova.edu/shss_dialogs/1016/thumbnail ...
Graduate School of Humanities & Social Sciences
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
https://nsuworks.nova.edu/shss_dialogs/1013/thumbnail ...
Graduate School of Humanities & Social Sciences
core +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Summary: The need for a compound risk governance system and management practice is argued in this paper. We find that, historically, risk management strategies have been developed for single hazards and are often subject to path dependency.
Thomas Thaler+3 more
doaj
https://nsuworks.nova.edu/shss_dialogs/1018/thumbnail ...
Graduate School of Humanities & Social Sciences
core +1 more source