Results 81 to 90 of about 6,448,019 (366)

Exploring informed consent in HIV clinical trials: A case study in Uganda

Heliyon, 2016
Introduction: In settings with low literacy levels ensuring that participants are fully-informed before they consent to participate in clinical trials is a challenge.
Agnes Ssali, Fiona Poland, Janet Seeley
doaj   +1 more source

Summer 2007 [PDF]

, 2007
https://nsuworks.nova.edu/shss_dialogs/1014/thumbnail ...
Graduate School of Humanities & Social Sciences
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Bluetooth-sensed social presence is associated with immediate vigor and delayed fatigue: A multi-method time series analysis

iScience
Summary: Social interactions affect emotional well-being, yet their temporal dynamics remain understudied in natural settings. We examined these patterns through an experience sampling method study with 80 participants over two weeks (k = 3,716 ...
David Willinger, Stefan Stieger
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Generative AI has lowered the barriers to computational social sciences [PDF]

, 2023
Yongjun Zhang
openalex   +1 more source

Spring 2011 [PDF]

, 2011
https://nsuworks.nova.edu/shss_dialogs/1005/thumbnail ...
Graduate School of Humanities & Social Sciences
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Science Librarianship and Social Justice: Part Three: Advanced Concepts

, 2021
Jeffra D. Bussmann, Isabel Altamirano, Samuel Hansen, Nastasha Johnson, Gr Keer   +4 more
openalex   +2 more sources

A 7,000-year-old multi-component arrow poison from Kruger Cave, South Africa

iScience
Summary: We present the results of a GC-MS and UHPLC-MS analysis of residue recovered from the marrow cavity of a 7,000-year-old bovid femur from Kruger Cave, South Africa.
Justin Bradfield, Ian A. Dubery, Paul A. Steenkamp   +2 more
doaj   +1 more source