Mapping Hsp104 interactions using cross‐linking mass spectrometry
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal+3 more
wiley +1 more source
How Preferences of General Medicine Students for Specialty Choice Are Affected? a qualitative study
How Preferences of General Medicine Students for Specialty Choice Are Affected? a qualitative study Heidari Mehdi1, Keivanara Mahmood2, Moeeni Maryam3* 1.
Mehdi Heidari+2 more
doaj
Generative Social Science: A Challenge [PDF]
openaire +3 more sources
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao+4 more
wiley +1 more source
Studying Welfare State from a Constructivist Perspective: Points of Departure for the Czech Case
The article uses the constructivist perspective and some approaches from the area of new institutionalism in order to reason over the possibilities and limits of the study of welfare state.
Martin Polášek, Vilém Novotný
doaj
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo+6 more
wiley +1 more source
GENERAL AND THEORETICAL: Mathematical Thinking in the Social Sciences. P
Frederick Mosteller
openalex +1 more source
The general framework of information awareness in higher education using ACRL standards: a field study on first-year students in the faculties of pure and applied sciences and the faculties of social sciences at Helwan University. [PDF]
Hebat Allah Soliman Othman El-Sayed
openalex +1 more source
Rethinking LLM Bias Probing Using Lessons from the Social Sciences [PDF]
The proliferation of LLM bias probes introduces three significant challenges: (1) we lack principled criteria for choosing appropriate probes, (2) we lack a system for reconciling conflicting results across probes, and (3) we lack formal frameworks for reasoning about when (and why) probe results will generalize to real user behavior.
arxiv
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source