Results 81 to 90 of about 398,723 (286)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Towards semantic enrichment for spatial interactions

Annals of GIS
Various big geo-data provide a social sensing approach to measure spatial interactions. Existing studies often aggregate individual-level movement trajectories or social ties to obtain the interaction intensity between places, neglecting the detailed ...
Yu Liu, Shengyin Wang, Xuechen Wang, Yunhao Zheng, Xiaojian Chen, Yang Xu, Chaogui Kang   +6 more
doaj   +1 more source

Geo-Tagged Social Media Data-Based Analytical Approach for Perceiving Impacts of Social Events

ISPRS International Journal of Geo-Information, 2018
Studying the impact of social events is important for the sustainable development of society. Given the growing popularity of social media applications, social sensing networks with users acting as smart social sensors provide a unique channel for ...
Ruoxin Zhu, Diao Lin, Michael Jendryke, Chenyu Zuo, Linfang Ding, Liqiu Meng   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Urban Spatial Heat Resilience Indicator Based on Running Activity Z-Score

Urban Science
The assessment of urban heat resilience has become crucial due to increasing extreme weather events. This study introduces the Running Activity Z-score (RAZ) index based on running activity trajectory data to evaluate heat resilience.
Li Zhou, Yuan Lai
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Using social media to measure impacts of named storm events in the United Kingdom and Ireland

Meteorological Applications, 2020
Despite increasing use of impact‐based weather warnings, the social impacts of extreme weather events lie beyond the reach of conventional meteorological observations and remain difficult to quantify.
M. Spruce, R. Arthur, H. T. P. Williams
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Urban Functional Zone Identification Based on Multimodal Data Fusion: A Case Study of Chongqing’s Central Urban Area

Remote Sensing
Urban Functional Zones (UFZs) are spatial units of the city divided according to specific functional activities. Detailed identification of UFZs is vital for optimizing urban management, guiding planning and design, and promoting sustainable development.
Yongchuan Zhang, Yuhong Xu, Jie Gao, Zunya Zhao, Jing Sun, Fengyun Mu   +5 more
doaj   +1 more source

An IEEE value loop of human-technology collaboration in geospatial information science

Geo-spatial Information Science, 2020
Geosensing and social sensing as two digitalization mainstreams in big data era are increasingly converging toward an integrated system for the creation of semantically enriched digital Earth.
Liqiu Meng
doaj   +1 more source