Results 101 to 110 of about 398,723 (286)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Social sensing the 2018 Kīlauea Volcanic eruption through community Facebook use

open access: yesVolcanica
There is a lack of understanding around the impacts and responses of communities receiving hazard and risk information during volcanic crises, but social media posts may be able to provide valuable insights.
Annie Matthews, James Hickey
doaj   +1 more source

@choo: Tracking Pollen and Hayfever in the UK Using Social Media

open access: yesSensors, 2018
Allergic rhinitis (hayfever) affects a large proportion of the population in the United Kingdom. Although relatively easily treated with medication, symptoms nonetheless have a substantial adverse effect on wellbeing during the summer pollen season ...
Sophie Cowie   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Transformer-Based Multimodal Model for Urban–Rural Fringe Identification

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
As the frontier of urbanization, urban–rural fringes (URFs) transitionally connect urban construction regions to the rural hinterland, and its identification is significant for the study of urbanization-related socioeconomic changes and human ...
Furong Jia   +9 more
doaj   +1 more source

Earth Observations in Social Science Research for Management of Natural Resources and the Environment: Identifying the Contribution of the U.S. Land Remote Sensing (Landsat) Program [PDF]

open access: yes
This paper surveys and describes the peer-reviewed social science literature in which data from the U.S. land remote sensing program, Landsat, inform public policy in managing natural resources and the environment.
Macauley, Molly K.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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