Results 41 to 50 of about 14,902,157 (256)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Towards Computer Simulations of Virtue Ethics
Open Philosophy, 2019 This article presents two approaches for computer simulations of virtue ethics in the context of agent-based modeling, a simple way and a complex way.
Lasquety-Reyes Jeremiah A.
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Enhancing the Realism of Simulation (EROS):On Implementing and Developing Psychological Theory in Social Simulation [PDF]
, 2017 Using psychological theory in agent formalisations is relevant to capture behavioural phenomena in simulation models (Enhance Realism Of Simulation - EROS).
Wander Jager, Jager, Wander
core +1 more source
Explaining Social Change: An Analytical Approach
Papers, 2006 Analytical sociology is a middle-range approach to sociological theorizing which seeks to develop precise and realistic action-based explanations of various social phenomena.
Peter Hedström
doaj +1 more source
Connecting livestock disease dynamics to human learning and biosecurity decisions
Frontiers in Veterinary Science, 2023 The acceleration of animal disease spread worldwide due to increased animal, feed, and human movement has driven a growing body of epidemiological research as well as a deeper interest in human behavioral studies aimed at understanding their ...
Gabriela Bucini +17 more
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Representing Dynamic Social Networks in Discrete Event Social Simulation [PDF]
, 2010 Proceedings of the 2010 Winter Simulation Conference B. Johansson, S. Jain, J. Montoya-Torres, J. Hugan, and E. Yücesan, eds.One of the key structural components of social systems is the social network. The representation of this network structure is key
Lieberman, Stephen, Alt, Jonathan K.
core +3 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2010 In this work simulation-based and analytical results on the emergence steady states in traffic-like interactions are presented and discussed. The objective of the paper is twofold: i) investigating the role of social conventions in coordination problem ...
Campenni, Marco, +7 more
core +1 more source