Results 161 to 170 of about 5,074,861 (337)

Deterministic Blockmodeling of Two-Mode Binary Networks Using a Two-Mode KL-Median Heuristic [PDF]

Journal of Social Structure, 2018
Michael Brusco, Hannah J. Stolze, Michaela Hoffman, Douglas Steinley, Patrick Doreian   +4 more
doaj   +1 more source

Rich cities, poor countryside? Social structure of the poor and poverty risks in urban and rural places in an affluent country. [PDF]

Local Econ, 2022
Hümbelin O, Hobi L, Fluder R.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Invisible Contours of Online Dating Communities: A Social Network Perspective [PDF]

Journal of Social Structure, 2017
Diane H. Felmlee, Derek A. Kreager
doaj   +1 more source

Theme editorial: What should be the role of tourism education social structures to create and support collaborative learning environments and the tourism sector? [PDF]

Hale Özgit, Ali Öztüren
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The effect of social structure on vocal flexibility in monk parakeets. [PDF]

R Soc Open Sci
Smeele SQ, Senar JC, McElreath MB, Aplin LM.   +3 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Elevated virus infection of honey bee queens reduces methyl oleate production and destabilizes colony-level social structure. [PDF]

Proc Natl Acad Sci U S A
McAfee A, Chapman A, Alcazar Magaña A, Marshall KE, Hoover SE, Tarpy DR, Foster LJ.   +6 more
europepmc   +1 more source

Organized to learn: the influence of social structure on social learning opportunities in a group. [PDF]

iScience, 2021
van Boekholt B, van de Waal E, Sterck EHM.   +2 more
europepmc   +1 more source