Results 121 to 130 of about 9,012,871 (307)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Picturing Teacher Agency: Developing Upstanding Heuristics in a Middle Grades Social Studies Methods Course [PDF]

open access: yes, 2019
This paper presents a multi-case study of teacher candidates in a pre-service middle grades social studies methods course. The research aimed to understand how the middle grades teacher candidates viewed their future as upstanders with agency in middle ...
Farley, Jennifer, Gallagher, Jennifer L
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Human aggression (Part 3) [PDF]

open access: yes, 2012
This theory sees aggression as social learning. According to social learning theories in earlier studies, people acquire aggressive responses the same way they acquire other complex forms of social behavior which either by direct experience or by ...
Jumat, Rahiman
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

İlköğretim 6. ve 7. Sınıf Sosyal Bilgiler Öğretim Programının Öğrenci Görüşlerine Göre Değerlendirilmesi Konya İli Örneği

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2009
Bu araştırmada 2005 sosyal bilgiler programının öğrenci görüşlerine göre değerlendirilmesi amaçlanmıştır. Araştırmanın evreni, Türkiye Cumhuriyeti Millî Eğitim Bakanlığı’na bağlıKonya ilindeki ilköğretim okullarında sosyal bilgiler dersini alan 6.
Hakan Akdağ
doaj  

A Systematic Review of ICT Integration in the Teaching and Learning of Social Sciences

open access: yesActa Educationis Generalis
Introduction: With the growing trend of technology adoption in teaching and learning, this integration must continuously be studied to track its status.
Nxusa Nokulunga Phathiswa   +2 more
doaj   +1 more source

The Design and Evaluation of an Interactive Social Engineering Training Programme [PDF]

open access: yes, 2016
Social engineering is a major issue affecting organisational security. Educating employees on how to avoid social engineering attacks is important because social engineering tries to penetrate an organisation by using employees to grant authorized ...
Alkhamis, Esra, Renaud, Karen
core  

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