Results 71 to 80 of about 5,017,199 (310)
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
مجلة الدراسات الاجتماعيةThis study examines the perceptions, practices, and challenges of small-scale farmers in the Afigya-Kwabre District regarding their role in eradicating hunger, with the Sustainable Livelihoods Framework (SLF) as the theoretical underpinning.
Isaac Eshun +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Living on the Edge: Social Exclusion and the Receipt of Informal Care in Older People
Journal of Aging Research, 2016 Older people have been identified as being at risk of social exclusion. However, despite the fact that care is commonly required in later life and the majority of that care is provided by informal carers, a connection between social exclusion and ...
Lena Dahlberg, Kevin J. McKee
doaj +1 more source
Social Mobility in Latin America: A Review of Existing Evidence [PDF]
This paper reviews evidence on social mobility in Latin America. Several studies have used data sets that collect intergenerational socio economic information.
Cesar Bouillon, Viviane Azevedo
core
Hospitality studies and hospitality management: a symbiotic relationship [PDF]
, 2008 The key contribution of this paper is to critically analyse advances made since the introduction of hospitality as a higher education subject, to capture contemporary thinking, and to support the recognition of the intellectual benefits for hospitality ...
Morrison, Alison, O'Gorman, Kevin D.
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
International Journal of Ageing and Later LifePrevious studies suggest that older adults from minority linguistic groups are at a higher risk of experiencing social exclusion, with service exclusion being a highly evident form.
Emilia Häkkinen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source