Results 101 to 110 of about 22,021,691 (406)
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Investigating the relationship between social support and durable return to work [PDF]
, 2015 The aim of the current study was to investigate the relationship between social support and durable return to work (RTW) post occupational injury. A total of 1,179 questionnaires were posted to clients previously receiving vocational rehabilitation ...
Cacciola, Tony +6 more
core +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Educating Students with Autism Spectrum Disorders: Organizational Problems
Психологическая наука и образование, 2016 The article presents data of applied socio-psychological research devoted to the study of difficulties encountered by educational institutions when teaching children with autism spectrum disorders (ASD).
Samsonova E.,, Alekseeva M.N.,
doaj +1 more source
Aging and social support [PDF]
, 2007 textabstractThis entry describes the concept of social support and provides an overview of the mechanisms through which it contributes to a healthy and long life. It draws on the task-specificity and the hierarchical compensation models to explain differences in the availability of social support in late life.
openaire +3 more sources
A study gauging perceived social support and loneliness with life satisfaction among students of Golestan University of Medical Sciences [PDF]
, 2010 Introduction: Social humans are embedded with a variety of relationships. Satisfactory social support is crucial for having physical and psychological well being.
Shahini, N.
core
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic +2 more
wiley +1 more source
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Participation Questionnaire for Preschoolers With Autism Spectrum Disorder: Item Development
Occupational Therapy InternationalOccupational therapists need to comprehensively assess the participation of children with autism spectrum disorder (ASD) in daily activities and evaluate the effectiveness of relevant interventions.
Takuto Nakamura +3 more
doaj +1 more source
Transforming Development with Grassroots Planning in Madhya Pradesh, India
Commonwealth Journal of Local Governance, 2012 There is growing acknowledgment that state interactions must take place in a democratic context. This has been accompanied by attempts to foster forms of democratic governance that provide scope for citizen participation in the development process ...
Yogesh Mahor, Ram Gopal Singh
doaj +1 more source