Results 91 to 100 of about 12,087,707 (288)

Bridging the gap between social tagging and semantic annotation: E.D. the Entity Describer [PDF]

, 2007
Semantic annotation enables the development of efficient computational methods for analyzing and interacting with information, thus maximizing its value.
Benjamin M. Good, Mark D. Wilkinson, Edward A. Kawas   +2 more
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Edutags als Referatory und "Suchmaschine" für Open Educational Resources

Zeitschrift für Hochschulentwicklung, 2013
Der Social-Bookmarking-/Social-Tagging-Dienst Edutags vom Learning Lab der Universität Duisburg-Essen und dem Deutschen Bildungsserver wird anhand von drei Modellen, in denen Optionen für das Aggregieren und Auffinden von Open Educational Resources (OER)
Ingo Wolfgang Blees, Richard Heinen
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Factors Affecting Mobile Tagging Awareness; A Research on Social Media Consumers

Journal of Economic Development, Environment and People, 2014
The purpose of the study is to identify the factors affecting awareness of mobile tagging on social media. The study assumes that the mobile tagging awareness levels of social media consumers are high.
Kübra DALDAL, Sabiha KILIÇ
doaj  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

DC-Social Tagging Workshop

, 2009
[Extract] 1. Introduction The so-called Web 2.0 brought a new breadth to the Internet, and a social perspective that seems set to stay. Services such as LinkedIn, Hi5, and Facebook have found a place in our society. People connect to each other through common paths.
Méndez, Eva, Baptista, Ana Alice
openaire   +3 more sources

Desvio e estetização da violência: Uma abordagem sócio-antropológica acerca da atividade dos pichadores de muros no Rio de Janeiro

Dilemas: Revista de Estudos de Conflito e Controle Social, 2012
O presente trabalho parte de dados empíricos colhidos em pesquisa etnográfica realizada no estado do Rio de Janeiro entre 2005 e 2007 e propõe uma abordagem sociológica das motivações que determinam o ingresso de jovens na atividade de pichação de muros ...
David da Costa Aguiar de Souza
doaj  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source