Results 71 to 80 of about 13,214 (262)
Revista de Estudios e Investigación en Psicología y Educación, 2015 Se exponen aquí los resultados de una experiencia educativa mediada con TIC donde jugó un papel relevante el empleo del etiquetado social o conjuntos de etiquetas creadas por múltiples usuarios en espacios web 2.0.
Francisco José Santos-Caamaño +1 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Profiling Social Networks: A Social Tagging Perspective
D-Lib Magazine, 2009 The web is rapidly becoming both more open and more social through the provision of technologies that make it easier for end users to access resources and join in social networks. Social networks have pioneered online communities, allowing users to contribute to collective knowledge by tagging online resources.
Ying Ding 0001 +4 more
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Elements of social representation theory incollaborative tagging systems
Transinformação, 2014 This article discusses the information representation process based on the Moscovici's Social Representation Theory and domain analysis in Information Science.
Patricia Zeni Marchiori +4 more
doaj
Edutags als Referatory und "Suchmaschine" für Open Educational Resources
Zeitschrift für Hochschulentwicklung, 2013 Der Social-Bookmarking-/Social-Tagging-Dienst Edutags vom Learning Lab der Universität Duisburg-Essen und dem Deutschen Bildungsserver wird anhand von drei Modellen, in denen Optionen für das Aggregieren und Auffinden von Open Educational Resources (OER)
Ingo Wolfgang Blees, Richard Heinen
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
, 2009 [Extract] 1. Introduction The so-called Web 2.0 brought a new breadth to the Internet, and a social perspective that seems set to stay. Services such as LinkedIn, Hi5, and Facebook have found a place in our society. People connect to each other through common paths.
Méndez, Eva, Baptista, Ana Alice
openaire +3 more sources
Social tagging in community memories
, 2008 Trabajo presentado al AAAI Spring Symposium celebrado en Stanford, California (US) del 26 al 28 de marzo de 2008.
Steels, Luc, Tisselli, Eugenio
openaire +3 more sources