Results 81 to 90 of about 115,508 (292)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Environmental Enrichment Induces Changes in Long-Term Memory for Social Transmission of Food Preference in Aged Mice through a Mechanism Associated with Epigenetic Processes

Neural Plasticity, 2018
Decline in declarative learning and memory performance is a typical feature of normal aging processes. Exposure of aged animals to an enriched environment (EE) counteracts this decline, an effect correlated with reduction of age-related changes in ...
Simona Cintoli, Maria Cristina Cenni, Bruno Pinto, Silvia Morea, Alessandro Sale, Lamberto Maffei, Nicoletta Berardi   +6 more
doaj   +1 more source

Semantic Editions of Classical Texts: How Social Networks Change Cognitive Strategies of Interaction with Literary Heritage

Виртуальная коммуникация и социальные сети, 2023
The paper introduces the phenomenon of semantic editions: a new digital representation of texts and personalities of the Great Literature, e. g., The World of Dante, Mapping the Republic of Letters, Chekhov Digital, Tolstoy Digital, and Pushkin Digital ...
Anastasia V. Kolmogorova
doaj   +1 more source

Content Reuse and Interest Sharing in Tagging Communities [PDF]

, 2008
Tagging communities represent a subclass of a broader class of user-generated content-sharing online communities. In such communities users introduce and tag content for later use.
Iamnitchi, Adriana, Ripeanu, Matei, Santos-Neto, Elizeu   +2 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Design and Implementation of an Online Social Network with Face Recognition

Journal of Advances in Information Technology, 2010
This paper presents the idea of an online social network that makes use of the face recognition technology. With the technology, friend relationship can be established without the need of having the text-based information of a user, friend recommendation
Ray K. C. Lai, Jack C. K. Tang, Angus K. Y. Wong, Philip I. S. Lei   +3 more
doaj   +1 more source

From news to comment: Resources and benchmarks for parsing the language of web 2.0 [PDF]

, 2011
We investigate the problem of parsing the noisy language of social media. We evaluate four all-Street-Journal-trained statistical parsers (Berkeley, Brown, Malt and MST) on a new dataset containing 1,000 phrase structure trees for sentences from ...
Cetinoglu, Ozlem, Foster, Jennifer, Hogan, Deirdre, Le Roux, Joseph, Nivre, Joakim, van Genabith, Josef, Wagner, Joachim   +6 more
core   +3 more sources

Good tags - bad tags. Social Tagging in der Wissensorganisation

, 2008
Münster u.a. : Waxmann 2008, 234 S. - (Medien in der Wissenschaft; 47)
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Solving the Cold-Start Problem in Recommender Systems with Social Tags

, 2010
In this paper, based on the user-tag-object tripartite graphs, we propose a recommendation algorithm, which considers social tags as an important role for information retrieval.
Liu, Chuang, Zhang, Yi-Cheng, Zhang, Zi-Ke, Zhou, Tao   +3 more
core   +1 more source