PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
The Cognitive-Affective-Social Theory of Learning in digital Environments (CASTLE). [PDF]
Schneider S +4 more
europepmc +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Educational Journeys Through Time: Overview and Impacts
This paper examines the profound impact of travel on educational experiences considering contemporary and historical journeys. It highlights the intricate relationship between education and experience, emphasizing their continued relevance in the context
Sanja Iguman Glušac +2 more
doaj +1 more source
Harnessing Bourdieu's social theory to understand the deteriorating doctor-patient-nurse relationship in West Bengal government hospitals. [PDF]
Sarkar T.
europepmc +1 more source
تصور مقترح قائم على نظرية مونتيسوري لتنمية المهارات الاجتماعية المتضمنة بمنهج الدراسات الاجتماعية وخفض حدة التنمر لدى تلاميذ المرحلة الابتدائية A proposed vision based on the Montessori theory to develop social skills included in the social studies curriculum and reduce the severity of bullying among primary school students [PDF]
شيماء شعبان حسين عبد العال +2 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Theory on the other Side of the Veil: Reckoning with Legacies of Anti-Blackness and Teaching in Social Theory. [PDF]
Fillingim A, Rucks-Ahidiana Z.
europepmc +1 more source
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source

