Results 121 to 130 of about 5,702,498 (304)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Educational Journeys Through Time: Overview and Impacts
Etnoantropološki ProblemiThis paper examines the profound impact of travel on educational experiences considering contemporary and historical journeys. It highlights the intricate relationship between education and experience, emphasizing their continued relevance in the context
Sanja Iguman Glušac +2 more
doaj +1 more source
Theory on the other Side of the Veil: Reckoning with Legacies of Anti-Blackness and Teaching in Social Theory. [PDF]
Am Sociol, 2021 Fillingim A, Rucks-Ahidiana Z.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Statement for Social Theory Caucus [PDF]
, 1980 In 1959, when C. Wright Mills made the statement quoted above, the dominant pathway to insight about human behavior was psychological. This situation appears to have been as true in art education as in any other discipline.
Lanier, Vincent
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Institutional matrices theory as a framework for both western and non-western people to understand the global village” [PDF]
Neither criticising Western social theory nor constructing an alternative kind of social theory is currently being thought of as a creative and fruitful method for social theorizing around the world today.
Kirdina, Svetlana, Sandstrom, Gregory
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Needs-Based Partial Theory of Human Injustice: Oppression, Dehumanization, Exploitation, and Systematic Inequality in Opportunities to Address Human Needs [PDF]
, 2019 The article presents an original needs-based partial theory of human injustice and shows its relationship to existing theories of human need and human liberation.
Dover, Michael Alan
core +3 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source