Results 141 to 150 of about 1,363,241 (318)
Social Engagement, Political Emotions, and Social Change
The main aim of the text is to address the formation of collective affective experiences in the time of crisis, which may or may not lead to social change. I would argue that during social crises there is the potential for the formation of (ephemeral)
Cvejić, Igor
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
, 2011 The overall aim of this article is to present a resource-based definition of social capital for health research that bridges the two notions of the concept the individual and the collective.
Rostila, Mikael,, Mikael Rostila
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
On the Principles of a Social Theory [PDF]
, 2018 This paper addresses the problem of how to identify a small and parsimonious set of principles or “postulates” that may help us understand the great theoretical foundations of the social sciences.
Carlos Blanco
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A tale of two theories: A critical comparison of identity theory with social identity theory
, 1995 Identity theory and social identity theory are two remarkably similar perspectives on the dynamic mediation of the socially constructed self between individual behavior and social structure.
Terry, Deborah J. +2 more
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Advancing Research on Character Assassination and Stigma Communication: A Dynamics of Character
, 2021 Documented occurrences of character assassination and stigmatization like those seen during the COVID-19 outbreak are not unique to the era of COVID-19. In fact, these forms of communication are ancient and ubiquitous in human society.
Smith, Rachel A, Eberly, Rosa A.
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source