Results 131 to 140 of about 1,363,241 (318)

A deliberative solution to the social choice problem [PDF]

, 2011
Is there a sense in which society makes rational decision in a democratic way that is similar to individual rational decision-making? Social choice theory claims that rational social choice is not possible.
Mladenović Ivan, Mladenović, Ivan, Ivan Mladenovic   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Cyber blame and social theory. [PDF]

SN Soc Sci, 2021
Hanson B.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

European Journal of Social Theory

European Journal of Social Theory (EJST), edited by Gerard Delanty, is a peer reviewed quarterly journal that publishes original articles in social theory. It is interdisciplinary in scope and international in its appeal to scholars anywhere in the world.
Monica Sassatelli
core  

Social and Geographical Distribution of Mobility-Related Greenhouse Gas Emissions in Poznań and Tri-City Functional Urban Areas

Quaestiones Geographicae
Mobility is an important source of greenhouse gas (GHG) emissions and a major contributor to human-induced climate change. Much of these emissions result from urban residents’ travel within urban areas (i.e.
Czepkiewicz Michał, Brudka Cezary, Krysiński Dawid, Schmidt Filip   +3 more
doaj   +1 more source

Growing decision-making: the role of theory of mind, empathy, and personality traits in school-age children

Frontiers in Psychology
Children’s decision-making is a socio-cognitive skill embedded within a broader system that promotes understanding of others and effective management of interpersonal contexts, making it closely linked to Theory of Mind (ToM) and empathy.
Elisabetta Lombardi, Cinzia Di Dio, Ilaria Castelli, Davide Massaro, Antonella Marchetti, Annalisa Valle   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Podcasting in Serbia: Podcasters’ Perspectives on Emerging Roles, Practices, and Functions

Media and Communication
Podcasting has become increasingly popular in Serbia, a hybrid regime country characterized by profound polarization, a lack of media professionalism, and widespread anti-press sentiment.
Simona Žikić, Čedomir Markov
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source