Results 151 to 160 of about 33,424,397 (335)

Modelando tiempo y espacio

open access: yesRevista de Ciencias Economicas, 2008
En este artículo se elaboran modelos de las ideas de tiempo y espacio social de Anthony Giddens o, por lo menos, compatibles con ellas. Hacia tal efecto, se aplican instrumentos gráficos y matemáticos para combinar conceptos cualitativos y cuantitativos,
Róger Churnside Harrison
doaj  

Social violence: Time to Innovate [PDF]

open access: yesSurgical Innovation, 2017
Lee L, Swanström, Adrian, Park
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

科舉文明:被視為臺灣教育改革阻力的文化 Civil Service Examination Civilization: The Culture of the Resistance to the Taiwan Educational Reforms

open access: yes臺灣教育社會學研究, 2010
本文旨在建立「科舉文明」這一理念型概念,以做為解釋反對教改諸種議題相關的社會結構基礎。透過科舉制度的傳統,教育與社會地位/階級/關係/家庭主義的教條之關係被緊密相連起來。雖然臺灣社會正在變遷當中,但是教改所威脅到的科舉考試傳統仍被視為是反抗教改之社會解釋的基礎。本研究發現,升學主義並不是迷信,而是科舉文明豐富內涵之中的一項行動機制,而升學考試制度則是國家與人民在政治經濟學上精算的結果。 In this article the grounds for a social explanation of ...
林民程 Min-Cheng Lin
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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