Results 131 to 140 of about 2,982,709 (316)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
TEMPORAL CHARACTERISTICS AND CONTRADICTIONS OF STUDENT YOUTH
Student youth is considered as a specific age community. Its development has inherent temporal characteristics and complex temporal contradictions.
Polina A. Ambarova, Garold E. Zborovsky
doaj
Social Housing and Homelessness Policies : reconciling social justice and social mix?
Whilst housing policies already had a distinctive Scottish flavour even before devolution, the creation of the Scottish Parliament in 1999 has allowed further policy-divergence (see for example, Maclennan and O’Sullivan 2008).
McKee, Kim, Phillips, Danny
core
Social development is about putting people at the centre of development. Since the 1990s there has been growing recognition that social development is critical for broader development outcomes, including sustainable economic growth.
Staveren, Prof. Dr. I. van (Erasmus University Rotterdam, International Institute of Social Studies) DAI=info:eu-repo/dai/nl/095049207
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Scottish Social Attitudes Survey, 2002
copyright UK Data Service and data collection copyright owner.The Scottish Social Attitudes (SSA) survey was launched by ScotCen Social Research (formerly the Scottish Centre for Social Research) in 1999, following the advent of devolution.
National Centre for Social Research
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Killing (Life)Time: A study on the Experience of Time in Prision
Prison emerged in its early forms in Europe in the mid 16th century and it spread together with capitalism. It operates by imposing to the individual a particular rigid time regime in an extremely limited spatial environment.
Pablo Leandro Ciocchini
doaj
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source

