Results 151 to 160 of about 2,982,709 (316)

Scottish Social Attitudes Survey, 2003

, 2005
copyright UK Data Service and data collection copyright owner.The Scottish Social Attitudes (SSA) survey was launched by ScotCen Social Research (formerly the Scottish Centre for Social Research) in 1999, following the advent of devolution.
Scottish Centre for Social Research
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Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Modelando tiempo y espacio

Revista de Ciencias Economicas, 2008
En este artículo se elaboran modelos de las ideas de tiempo y espacio social de Anthony Giddens o, por lo menos, compatibles con ellas. Hacia tal efecto, se aplican instrumentos gráficos y matemáticos para combinar conceptos cualitativos y cuantitativos,
Róger Churnside Harrison
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Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

科舉文明：被視為臺灣教育改革阻力的文化 Civil Service Examination Civilization: The Culture of the Resistance to the Taiwan Educational Reforms

臺灣教育社會學研究, 2010
本文旨在建立「科舉文明」這一理念型概念，以做為解釋反對教改諸種議題相關的社會結構基礎。透過科舉制度的傳統，教育與社會地位／階級／關係／家庭主義的教條之關係被緊密相連起來。雖然臺灣社會正在變遷當中，但是教改所威脅到的科舉考試傳統仍被視為是反抗教改之社會解釋的基礎。本研究發現，升學主義並不是迷信，而是科舉文明豐富內涵之中的一項行動機制，而升學考試制度則是國家與人民在政治經濟學上精算的結果。 In this article the grounds for a social explanation of ...
林民程 Min-Cheng Lin
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Peace/time landscape proposals for the Israeli and Palestinian border

, 2011
This thesis began with a consideration of time in landscape architecture. Design practices in landscape architecture are usually open-ended in terms of time, but a prevalent new condition, the shrinking scale of social time, provides opportunities for ...
Wu, Shuangshuang
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