Results 71 to 80 of about 2,613,172 (306)

Extracorporeal carbon dioxide removal for the treatment of acute hypoxaemic respiratory failure: the REST RCT

Health Technology Assessment
Background In patients who require mechanical ventilation for acute hypoxaemic respiratory failure, further reduction in tidal volumes, compared with conventional low tidal volume ventilation, may improve outcomes.
James J McNamee, Ashley Agus, Andrew J Boyle, Colette Jackson, Cliona McDowell, Jeanette Haglund, Danny F McAuley   +6 more
doaj   +1 more source

Pediatric intraorbital abscess: Early recognition and management

Clinical Case Reports, 2019
Key Clinical Message Orbital involvement occurs in 85% of complicated acute sinusitis and is more prevalent in children. Prompt differentiation between the more common periorbital (preseptal) cellulitis and infections, posterior to the orbital septum ...
Dominic McKenna, Ekambar Reddy, Eugene McKenna   +2 more
doaj   +1 more source

Trust and Social Collateral [PDF]

This paper builds a theory of informal contract enforcement in social networks. In our model, relationships between individuals generate social collateral that can be used to control moral hazard when agents interact in a borrowing relationship.
Adam Szeidl, Markus Mobius
core  

Designing the past: the National Trust as a social-material agency [PDF]

, 2009
The National Trust was founded in 1895 for ‘the preservation of places of historic interest or natural beauty’. While the distinction between the cultural and the natural seemed obvious at that time and members and visitors were not even implicated ...
Fox, Dorothy, Johnston, Nicky, Wallace, Stephen   +2 more
core  

Social capital, institutions and trust [PDF]

Review of Social Economy, 2006
This paper analyzes the relations between social capital, institutions and trust.These concepts are full of ambiguity and confusion.This paper attempts to dissolve some of the confusion, by distinguishing trust and control, and analyzing institutional and relational conditions of trust.It presents a tool for the analysis of the foundations of trust and
openaire   +5 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Prescription practices for antipsychotic medication in an acute inpatient ward: Risks / benefits discussions with patients and performance of baseline investigations as per NICE guidelines

European Psychiatry
Introduction Antipsychotic medications are essential for managing psychiatric disorders, offering symptom relief and improved functioning. However, their use carries potential risks.
M. Elesawy, G. J. Munday, N. Lekka
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The management of COVID-19 in prisons – the case of Northern Ireland

Health & Justice
Background This paper describes COVID-19 cases in the Northern Ireland (NI) prison population during the pandemic in relation to the general population and changes implemented to control infection in NI prisons.
Dermot O’Reilly, Janine Cooper, Rosie Murphy, Aideen Maguire, Richard Kirk, Trish Kelly, Ruth Gray, Stephen McGarrigle, Julie Anderson, Michael Donnelly   +9 more
doaj   +1 more source

Trust (Social Science)

, 2022
rust is the willingness of one party (the trustor) to become vulnerable to another party (the trustee) on the presumption that the trustee will act in ways that benefit the trustor.
openaire   +1 more source