Results 91 to 100 of about 188,750 (294)
Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
wiley +1 more source
Advanced Biology, EarlyView.This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen +4 more
wiley +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Vulnerabilidade Socioambiental do Baixo Curso da Bacia Hidrográfica do Rio Cocó, Fortaleza-CE / Vulnerability Socioenvironmental of Down Progress of Cocó River’s Watershed, Fortaleza-CE (Brazil) [PDF]
Sociedade & Natureza, 2013 The following study is about the vulnerability environmental, social and socio environmental of downprogress of Coco river’s watershed, at Fortaleza-CE.
Maria Elisa Zanella +3 more
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Social Science Research Needs: Focus on Vulnerable Populations, Forecasting, and Warnings [PDF]
, 2007 Brenda D. Phillips, Betty Hearn Morrow
openalex +1 more source
Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics
Advanced Engineering Materials, EarlyView.Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani +2 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Hydrostatic bearings excel in high‐precision applications, but their performance hinges on a continuous external supply. This study evaluates various material combinations for sliding surfaces to mitigate damage during supply failures or misalignment and to discover the most effective materials identified for enhancing the reliability and efficiency of
Michal Michalec +6 more
wiley +1 more source
Fear responding to 35% CO2 challenge as a vulnerability marker for later social anxiety symptoms [PDF]
, 2007 Norman B. Schmidt +2 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Graded refractive index (GRI) structures are prepared from the layer‐by‐layer spray coating of the mesoporous SiO2 nanoparticles, showing high solar transparency and thermal emissivity. Under outdoor conditions, after 50 days, the GRI‐coated photovoltaics show on average 6.65 ± 1.48 °C lower than that of the non‐coated references, maintaining 80.9 ± 8 ...
Heesuk Jung +14 more
wiley +1 more source
Assessment of community vulnerability during the COVID-19 pandemic: Hong Kong as a case study
International Journal of Applied Earth Observations and Geoinformation, 2022 The COVID-19 pandemic continues to threaten global public health. Reliable assessment of community vulnerability is therefore essential to fighting and mitigating the pandemic.
Mengling Qiao, Bo Huang
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