Results 61 to 70 of about 188,750 (294)

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Infant Mortality in Socially Vulnerable Populations [PDF]

Annual Review of Public Health, 1988
Studies have shown for decades that certain subpopulations of infants, for example, those in poverty and in certain minority groups, are at substantially higher risk for illness and death than the national average. If mothers and infants of these “vulnerable populations” were as healthy as their “nonvulnerable” counterparts, as many as one third ...
openaire   +2 more sources

A theoretical and methodological essay on the concept of vulnerability / Un ensayo teórico y metodológico sobre el concepto de vulnerabilidad

Contexto: Revista de la Facultad de Arquitectura Universidad Autónoma de Nuevo León, 2018
This paper presents a bibliographical review on the concept and methods of identifying vulnerability in urban areas. From systematic bibliographic searches, the main concepts that orbit around vulnerability are defined, as well as their concretion ...
Antonio Palacios García, Pablo Mateos, Carmen Hidalgo Giralt   +2 more
doaj  

The structural relationships of social vulnerability of female heads of households based on critical thinking and social acceptance with the mediating role of self-esteem [PDF]

مطالعات اجتماعی روان‌شناختی زنان
Female-headed households face multiple challenges due to simultaneously fulfilling paternal and maternal roles. The present study aimed to investigate the structural relationships of social vulnerability based on critical thinking and social acceptance ...
Fatemeh Jadidi, Azadeh Choobforoushzadeh, Yasser Rezapour mirsaleh, Elaheh Shirovi   +3 more
doaj   +1 more source

SARS‐CoV‐2 Is Linked to Brain Volume Loss in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The impact of SARS‐CoV‐2 infection on brain and spinal cord pathology in patients with multiple sclerosis (pwMS) remains unclear. We aimed to describe changes in brain lesion activity and brain and spinal cord volumes following SARS‐CoV‐2 infection.
Tomas Uher, Dominika Stastna, Ingrid Menkyova, Vaclav Capek, Jiri Lindner, Petra Nytrova, Jan Krasensky, Eliza Varju, Miguel D'haeseleer, Eva Kubala Havrdova, Dana Horakova, Manuela Vaneckova, Niels Bergsland   +12 more
wiley   +1 more source

The Challenge of Coexistence in Socially Vulnerable Schools

Procedia - Social and Behavioral Sciences, 2017
Society in general and schools in particular continue to express their concerns with regard to the many challenges posed nowadays by living in a globalized world, where learning to coexist involves knowing oneself and those around us. Therefore, the professionals from the education sector and specially from the most vulnerable contexts demand the ...
García Raga, Laura, Grau Vidal, Roser, López Martín, Ramón   +2 more
openaire   +3 more sources

Lower social vulnerability is associated with a higher prevalence of social media-involved violent crimes in Prince George’s County, Maryland, 2018–2023

Injury Epidemiology
Background Social vulnerability may play a role in social media-involved crime, but few studies have investigated this issue. We investigated associations between social vulnerability and social media-involved violent crimes.
Jemar R. Bather, Diana Silver, Brendan P. Gill, Adrian Harris, Jin Yung Bae, Nina S. Parikh, Melody S. Goodman   +6 more
doaj   +1 more source

Amyotrophic Lateral Sclerosis as a Multistep Process in the United States: A Population‐Based Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease that typically results in death within 3–5 years from symptom onset. However, little is known about the environmental exposures, clinical aspects, or social determinants of health factors that may be associated with the disease.
Jasmine Berry, Jaime Raymond, Theodore Larson, D. Kevin Horton, Moon Han, Theresa Nair, Ammar Al‐Chalabi, Paul Mehta   +7 more
wiley   +1 more source

Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. Objective Explore the relationship between abnormal spontaneous resting‐state activity and atrophy in HD‐specific brain regions and ...
Yinghua Jing, Imis Dogan, Rena Theda Overbeck, Kathrin Reetz, Sandro Romanzetti   +4 more
wiley   +1 more source

The association of social vulnerability with colorectal enhanced recovery program failure

Surgery Open Science, 2023
Background: Enhanced recovery programs (ERPs) improve outcomes, but over 20 % of patients fail ERP and the contribution of social vulnerability is unknown.
Burkely P. Smith, MD, Robert H. Hollis, MD, MSPH, Connie C. Shao, MD, MSPH, Lauren Gleason, MD, Lauren Wood, MPSH, Marshall C. McLeod, MS, PhD, Danielle I. Kay, MD, Gabriela R. Oates, PhD, Maria Pisu, PhD, Daniel I. Chu, MD, MSPH, FACS, FASCRS   +9 more
doaj