Results 111 to 120 of about 464,495 (310)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Corruption Perception and Perceived Social Justice: upgrading the Administrative Integrity of Organizations and Improving the Citizens\' Perceived Justice [PDF]
مسائل اجتماعی ایران, 2016 The aim of this study is to examine the relationship between Perception of corruption and perceived social justice. This study is a cross-sectional survey. The target population was all Tehran residents, aged 18 to 60.
Mehdi Mohammadi +3 more
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Domains, Components and Indicators of Children’s Wellbeing in Iran: A Delphi Study
مجله اپیدمیولوژی ایران, 2018 Background and Objectives: Children’s well-being is a multidimensional construct that precedes various aspects of childrenchr('39')s lives. This study sought to identify the main areas of childrenchr('39')s wellbeing in Iran and their domains, components,
H Sajadi +4 more
doaj
CSWA overview and Endowment Campaign Launch
, 2015 2014 CSWA Endowment Campaign Launch and overview. Esther Gillies, CSWA Board President's, overview of the organization and the launch of the Preserving Our Social Welfare Heritage ...
California Social Welfare Archives
core
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
ASEAN Social Work JournalThe government's efforts to protect and empower women are realized through the School for Great Women model. The problem of the study is how the School for Great Women Model influence family resilience in Dano Indonesia Village.
Bambang Rustanto +3 more
doaj +1 more source
, 2014 2014 CSWA Awards Luncheon. 28th Annual California Social Welfare Archives Awards Reception Luncheon, Galen Center (3400 South Figueroa Street), University of Southern California, Los Angeles, 2014 April 2.
California Social Welfare Archives
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Nash Social Welfare Function [PDF]
Econometrica, 1979 Kaneko, Mamoru, Nakamura, Kenjiro
openaire +1 more source