Results 131 to 140 of about 12,444,881 (305)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Genetic Causes of Putative Autosomal Recessive Intellectual Disability Cases in Hamedan Province
Journal of Rehabilitation, 2012 Objective: The aim of this study was to investigate the genetic causes of autosomal recessive intellectual disabilities (AR-ID) in Hamadan province of Iran. Materials & Methods: In this descriptive-analytical cross-sectional study, 25 families with more
Milad Bastami +4 more
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Journal of Rehabilitation, 2015 Objective: Social protection is one of the most important predictors of people’s health. The aim of this study was to determine the relationship between social support and life quality, among disableds of Raad’s educational institutes.
Nasrin Khosravi-Tapeh +3 more
doaj
Death, social reform and the scrutiny of social welfare provision: the role of the contemporary inquest. [PDF]
J Soc Welf Fam Law, 2023 Kirton-Darling E.
europepmc +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
, 2014 1997 CSWA Awards Luncheon. 13th annual California Social Welfare Archives Awards Luncheon, 1997, honoring Rino J. Patti and Leah Cohn. Keynote address by Bruce Jansson entitled "Welfare reform: Lessons from the past". Also welcoming Dean Marilyn Flynn to
California Social Welfare Archives
core
Sālmand, 2015 Objectives Old age is a period of life in which elderly are exposed to potential threat. These factors lead to decreased quality of life in elderly. Social interaction is of the factors affecting the quality of life and health in the elderly. We aimed to
Mojtaba Laal Ahangar +2 more
doaj
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source