Results 151 to 160 of about 2,045,222 (347)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

New Social Policy Ideas in the Making: The Case of Central and Eastern Europe [PDF]

open access: yes
Central and Eastern European countries have experienced a rapid transformation of their economic, political and welfare regime(s). From a state-paternalist welfare state, post-communist countries are now moving towards something new.
Cerami, Alfio
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Optimal lockdown and social welfare. [PDF]

open access: yesJ Popul Econ, 2022
Pestieau P, Ponthiere G.
europepmc   +1 more source

Uniform pricing and social welfare [PDF]

open access: yes
We re-examine the case for uniform pricing in a monopolistic third-degree price-discrimination setting by introducing differentiated costs. A profit-maximizing monopolist could then use price differentiation to reduce the production of the more costly ...
Bertoletti, Paolo
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

The Effectiveness of Group Social Work Intervention with Resolving the Problem of Reducing Suicidal Ideation in Qorveh City

open access: yesJournal of Rehabilitation, 2019
Objective Suicide and suicidal behavior (suicidal ideation, suicidal plan, and suicidal act) as one of the major problems in the social and psychological health system is an important and significant issue around the world.
Pari Varmaghani   +3 more
doaj  

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