Results 91 to 100 of about 1,999,921 (311)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Do tolerant societies demand better institutions? [PDF]

open access: yes, 2019
The increasing ethnic heterogeneity that many societies are experiencing could be interpreted as a detrimental phenomenon, since empirical literature exists that indicates that higher levels of ethnic fractionalization induce higher levels of corruption.
Buitrago Esquinas, Eva María   +2 more
core   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

ШЕВЧЕНКІАНА КИЇВСЬКОЇ ГРОМАДИ ЯК СУСПІЛЬНО-НАУКОВИЙ ПРОСТІР

open access: yesПростір в історичних дослідженнях, 2023
У статті розглянуто аспекти, пов’язані з діяльністю Київської Громади як основного осередку українофільського руху другої половини ХІХ – початку ХХ ст. Зокрема, акцентується на науковому вивченні її представниками життя та творчості Т. Г.
Катерина Нагайко
doaj  

French Red Cross Ladies in International or Universal Exhibitions (1867–1937)

open access: yesFrontiers in Sociology, 2019
This paper attempts to pinpoint what French Red-Cross women were doing in the international exhibitions from 1867 to 1937. They engaged their energies into organizing meetings, exhibitions, and into healing, receiving awards for their work.
Corinne M. Belliard
doaj   +1 more source

Sudden Trust Collapse in Networked Societies

open access: yes, 2015
Trust is a collective, self-fulfilling phenomenon that suggests analogies with phase transitions. We introduce a stylized model for the build-up and collapse of trust in networks, which generically displays a first order transition.
Batista, João da Gama   +2 more
core   +3 more sources

Computational Evidence that Self-regulation of Creativity is Good for Society [PDF]

open access: yesProceedings of the 36th Annual Meeting of the Cognitive Science Society (pp. 2240-2245). Houston TX: Cognitive Science Society, 2014
Excess individual creativity can be detrimental to society because creators invest in unproven ideas at the expense of propagating proven ones. Moreover, a proportion of individuals can benefit from creativity without being creative themselves by copying creators. We hypothesized that (1) societies increase their rate of cultural evolution by tempering
arxiv  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Support Science by Publishing in Scientific Society Journals

open access: yesmBio, 2017
Scientific societies provide numerous services to the scientific enterprise, including convening meetings, publishing journals, developing scientific programs, advocating for science, promoting education, providing cohesion and direction for the ...
Patrick D. Schloss   +2 more
doaj   +1 more source

Fairness in society [PDF]

open access: yesarXiv, 2011
Models that explain the economical and political realities of nowadays societies should help all the world's citizens. Yet, the last four years showed that the current models are missing. Here we develop a dynamical society-deciders model showing that the long lasting economical stress can be solved when increasing fairness in nations.
arxiv  

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