Results 91 to 100 of about 18,424,379 (354)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Role of Education in the Development of Public Relations in the Modern Russia

open access: yesÈkonomika, Pedagogika i Pravo, 2016
In this article author showed influence of an education system on forming and development of public relations. The important role of education in the course of forming of civil society is noted.
Lubov I. Rogaceva
doaj  

Why Take A Language at GCSE [PDF]

open access: yes
Poster on why to take a foreign language at ...
Society, Shropshire Languages
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

SALT Equalizer, Vol. 2015, Issue 2

open access: yes, 2015
Contents of This Issue: 2016 SALT Annual Dinner, at 1. 2016 SALT Annual Dinner Sponsors, at 2. Olympia Duhart & Ruben Garcia, Co-Presidents’ Column, at 2. SALT Membership: Reduced Rates, Online Renewal, at 3. SALT Files Amicus Brief Supporting University
Society of American Law Teachers
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.

open access: yesEuropean Heart Journal-Cardiovascular Imaging, 2015
R. Lang   +17 more
semanticscholar   +2 more sources

Basic Issues of Management in the Field of Public Security

open access: yesZeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej, 2016
The issue of management in the area of public security is a subject under intensive research due to its importance for managing the security of the state.
Wojciech Wiśniewski
doaj  

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