Results 81 to 90 of about 15,402,540 (312)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Ohio Connecting to Collections survey results -- Crosstab by Institution Budget [PDF]
OhioSurvey MonkeyCrosstab of survey results showing results sorted by institution annual budgetInstitute of Museum and Library ServicesState Library of Ohio, Ohio Historical Society, Intermuseum Conservation Association, Ohio Museums Assocation, Ohio ...
Ohio Historical Society
core
Science,technology and society
, 2005 We shall discuss some aspects of science and technology, their increasing role in the society, the fast advances in modern science, the apparent decrease of interest of the young generation in basic sciences, the importance of proper science ...
Giacomelli, G., Giacomelli, R.
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Eigenmodes and thermodynamics of a Coulomb chain in a harmonic potential [PDF]
, 2004 The density of ions trapped in a harmonic potential in one dimension is not uniform. Consequently the eigenmodes are not phonons. We calculate the long wavelength modes in the continuum limit, and evaluate the density of states in the short wavelength ...
American Physical Society +2 more
core +3 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
, 2016 This document explains the PLACE theme at Linfield College for 2016-2018 (The Digital Society)
PLACE
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Two-photon and EIT-assisted Doppler cooling in a three-level cascade system [PDF]
, 2006 Laser cooling is theoretically investigated in a cascade three-level scheme, where the excited state of a laser-driven transition is coupled by a second laser to a top, more stable level, as for alkali-earth atoms.
American Physical Society +2 more
core +3 more sources