Results 111 to 120 of about 35,106 (263)

Recent Insights Into Circulating Adipokines in Obesity: Systematic Review and Meta‐Analysis

Obesity Science &Practice, Volume 12, Issue 1, February 2026.
ABSTRACT Background Adipokines are dysregulated in obesity and exacerbate proinflammatory conditions. Although several studies have investigated adipokine levels in obesity, their findings have been inconsistent, leaving the precise nature of these alterations uncertain.
Sunita Sunita, Mohammad Ghozali, Mohammad Rizki Akbar, Annisa Dewi Nugrahani, Iis Inayati Rakhmat, Siti Nur Fatimah, Yuni Susanti Pratiwi, Eko Fuji Ariyanto, Gaga Irawan Nugraha, Mas Rizky A. A. Syamsunarno, Tri Hanggono Achmad   +10 more
wiley   +1 more source

Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease [PDF]

, 2008
© 2008 Zhu et al. This article is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).Maintaining tolerance of T cells to self-antigens
Kioussis, Dimitris, Li, Suling, Martin, Joanne E., Symonds, Alistair L.J., Wang, Ping, Wraith, David C., Zhu, Bo   +6 more
core   +3 more sources

Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions

Aging Cell, Volume 25, Issue 2, February 2026.
Hematopoietic aging arises from intrinsic stem‐cell decline and bone‐marrow niche dysfunction, leading to myeloid skewing, immunosenescence, and clonal hematopoiesis. These changes drive systemic inflammation and multi‐organ disease, which in turn further disrupt the bone‐marrow niche and hematopoietic stem cell (HSC) function, creating a vicious cycle
Masashi Miyawaki, Seiji Hashimoto, Sumito Ogawa, Yoshitaka Kase   +3 more
wiley   +1 more source

Suppressor of cytokine signaling 3 (SOCS3) is not an independent biomarker of colorectal adenoma risk

BMC Research Notes, 2010
Background Inflammation and its associated pathologies are increasingly suggested as risk factors for colorectal cancer (CRC) development. Previous research from our group has shown that increased levels of circulating, pro-inflammatory cytokines IL-6 ...
Sandler Robert S, Galanko Joseph A, Lund P Kay, Hamilton Kathryn E, Keku Temitope O   +4 more
doaj   +1 more source

Galectin-1 is essential for efficient liver regeneration following hepatectomy [PDF]

, 2016
Galectin-1 (Gal1) is a known immune/inflammatory regulator which actsboth extracellularly and intracellularly, modulating innate and adaptive immuneresponses. Here, we explored the role of Gal1 in liver regeneration using 70% partial hepatectomy (PHx) of
Cerliani, Juan Pablo, Ella, Ezra, Galun, Eithan, Goldenberg, Daniel S., Mizrahi, Lina, Pappo, Orit, Potikha, Tamara, Rabinovich, Gabriel Adrián   +7 more
core   +1 more source

Comparative Study Showed Significant Gene Expression Differences in Newborn Infants After Vaginal and Caesarean Deliveries

Acta Paediatrica, Volume 115, Issue 2, Page 393-398, February 2026.
ABSTRACT Aim We aimed to investigate the impact of the delivery mode, comparing vaginal deliveries with elective Caesarean deliveries, on neonatal gene expression and immune system activation. By examining the differences in gene expression profiles and inflammatory markers in neonatal cord blood, the study sought to elucidate the biological processes ...
Noora Carpén, Otto Helve, Sabina Ericsson, Ilona Kervinen, Maija Stewart‐Linnonmaa, Santtu Heinonen, Sture Andersson, Emmi Helle   +7 more
wiley   +1 more source

Genetic Variation in the IL-6 and HLA-DQB1 Genes Is Associated with Spontaneous Clearance of Hepatitis C Virus Infection. [PDF]

, 2016
Background. Millions of people are infected with hepatitis C virus (HCV) worldwide and 30% spontaneously clear the infection. Reasons for HCV clearance without antiviral treatment are not well understood. Methods.
Belitskaya-Lévy, Ilana, Chary, Aarthi, Holodniy, Mark, Lazzeroni, Laura C, Monto, Alexander, Ryan, James, Waldron, Paul Ravi, Winters, Mark, Won, Johann   +8 more
core   +3 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Dysregulated circulating SOCS3 and haptoglobin expression associated with stable coronary artery disease and acute coronary syndrome: An integrated study based on bioinformatics analysis and case–control validation

Anatolian Journal of Cardiology, 2020
Objective: To extensively use blood transcriptome analysis to identify potential diagnostic and therapeutic targets for cardiovascular diseases. Methods: Two gene expression datasets (GSE59867 and GSE62646) were downloaded from GEO DataSets to identify ...
Xunnan Zhang, Xi Lv, Xiandong Li, Yaping Wang, Hao-yu Lin, Jicai Zhang, Chunyan Peng   +6 more
doaj   +1 more source

NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice [PDF]

, 2018
Innate lymphoid cells (ILCs) producing IL-22 and/or IL-17, designated as ILC3, comprise a heterogeneous subset of cells involved in regulation of gut barrier homeostasis and inflammation.
Kanno, Yuka, Mikami, Yohei, O'Shea, John J, Santoni, Angela, SCARNO, GIANLUCA, Sciumè, Giuseppe, Shih, Han-Yu, Zitti, Beatrice   +7 more
core   +1 more source