Results 241 to 250 of about 35,106 (263)

SOCS3 and its role in associated diseases

Human Immunology, 2015
Cell-cell communication depends on cytokine and growth factor network. Bound to their receptors on the surface of target cell, these glycoproteins initiate a range of intracellular events. Subsequent dissipation of receptor signaling is essential to ensure the response of the cell does not become pathogenic. The Suppressors of cytokine signaling (SOCS)
Yanlin, Yin, Weiwei, Liu, Yalei, Dai
openaire   +2 more sources

SOCS3 promotes apoptosis of mammary differentiated cells

Biochemical and Biophysical Research Communications, 2005
Growth and function of the mammary gland is regulated by cytokines and modulated by suppressor of cytokine signalling (SOCS) proteins. In vitro experiments demonstrated that SOCS3 can inhibit PRL induction of milk protein gene expression and STAT5 activation.
Le Provost, Fabienne   +5 more
openaire   +3 more sources

SOCS3 regulates the plasticity of gp130 signaling

Nature Immunology, 2003
Suppressor of cytokine signaling (SOCS) proteins are feedback inhibitors of the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) signaling pathway. SOCS3 is upregulated by several signals in macrophages and has been implicated as a regulator of various signaling pathways.
Roland, Lang   +7 more
openaire   +2 more sources

Hepatocyte growth control by SOCS1 and SOCS3

Cytokine, 2019
The extraordinary capacity of the liver to regenerate following injury is dependent on coordinated and regulated actions of cytokines and growth factors. Whereas hepatocyte growth factor (HGF) and epidermal growth factor (EGF) are direct mitogens to hepatocytes, inflammatory cytokines such as TNFα and IL-6 also play essential roles in the liver ...
Md Gulam Musawwir Khan   +6 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy