Results 51 to 60 of about 416,329 (251)

Perfluorooctanoic acid affects mouse brain and liver tissue through oxidative stress

Arhiv za Higijenu Rada i Toksikologiju, 2022
The aim of this study was to investigate oxidative stress induced by perfluorooctanoic acid (PFOA) in the brain and liver tissues of Balb/c mice as well as protective effects of taurine and coenzyme Q10 (CoQ10) in both organs.
Endirlik Burcu Ünlü, Eken Ayşe, Canpınar Hande, Öztürk Figen, Gürbay Aylin   +4 more
doaj   +1 more source

Inhibitors and Activators of SOD, GSH‐Px, and CAT

, 2017
Reactive oxygen species (ROS) is harmful to our health, and SOD, CAT, and GPX are the major antioxidant enzymes that defend us from effects of ROS. In medicine, food, and dairy industries, antioxidant enzymes often surround complex environments.
Xianyong Ma, D. Deng, Weidong Chen
semanticscholar   +1 more source

Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SODG93A mice co-expressing the Copper-Chaperone-for-SOD

Neurobiology of Disease, 2016
Over-expression of mutant copper, zinc superoxide dismutase (SOD) in mice induces ALS and has become the most widely used model of neurodegeneration. However, no pharmaceutical agent in twenty years has extended lifespan by more than a few weeks.
Jared R. Williams, Emiliano Trias, Pamela R. Beilby, Nathan I. Lopez, Edwin M. Labut, C. Samuel Bradford, Blaine R. Roberts, E. McAllum, P. Crouch, T. Rhoads, C. Pereira, M. Son, Jeffrey L. Elliott, Maria Clara Franco, Alvaro G. Estévez, L. Barbeito, Joseph S. Beckman   +16 more
semanticscholar   +1 more source

Bariatric–Metabolic Surgery: The State of the Art and the Management of Complications

Dietetics
Bariatric surgery is a highly effective therapeutic strategy in the treatment of severe obesity, but it carries significant risks, both in the short and long terms.
Silvia Tedesco, Nadia Campelli, Stefano Lunetti, Giulia Nicolai, Cristina Marmorale, Albano Nicolai, Marina Taus   +6 more
doaj   +1 more source

SOD Enzymes and Microbial Pathogens: Surviving the Oxidative Storm of Infection

PLoS Pathogens, 2016
Since oxygen appeared in the biosphere some 3–5 billion years ago, all organisms have had to deal with the hazards of potentially damaging reactive oxygen species (ROS), such as superoxide, hydrogen peroxide, and hydroxyl radical.
Chynna N. Broxton, V. Culotta
semanticscholar   +1 more source

Morphodynamic Features of Contrast-Enhanced Mammography and Their Correlation with Breast Cancer Histopathology

Journal of Imaging
Contrast-enhanced mammography (CEM) combines morphological and functional imaging, enhancing breast cancer (BC) diagnosis. This study investigates the relationship between CEM morphodynamic features and histopathological characteristics of BC.
Claudio Ventura, Marco Fogante, Elisabetta Marconi, Barbara Franca Simonetti, Silvia Borgoforte Gradassi, Nicola Carboni, Enrico Lenti, Giulio Argalia   +7 more
doaj   +1 more source

Contrast-Enhanced Mammography in Breast Cancer Follow-Up: Diagnostic Value in Suspected Recurrence

Journal of Imaging
Women with a personal history of breast cancer (PHBC) are at increased risk of local recurrence or new primary tumors, which are often difficult to assess on conventional imaging because of postoperative changes.
Claudio Ventura, Marco Fogante, Nicola Carboni, Silvia Gradassi Borgoforte, Barbara Franca Simonetti, Elisabetta Marconi, Giulio Argalia   +6 more
doaj   +1 more source

Protective Effects of Different Doses of Pycnogenol Extract against Gamma Radiation-induced Liver Damage in Rat

Erciyes Medical Journal, 2020
Objective: The study aims to investigate the protective role of pycnogenol extract against liver damage in whole-body gamma-irradiated rats by assessing DNA damage, histopathological changes and biochemical parameters.
Fazile Cantürk Tan, Arzu Hanım Yay, Oğuz Galip Yıldız, Yusuf Caner   +3 more
doaj   +1 more source

The role of cerium redox state in the SOD mimetic activity of nanoceria.

Biomaterials, 2008
Cerium oxide nanoparticles (nanoceria) have recently been shown to protect cells against oxidative stress in both cell culture and animal models. Nanoceria has been shown to exhibit superoxide dismutase (SOD) activity using a ferricytochrome C assay, and
Eric G Heckert, A. Karakoti, S. Seal, W. Self   +3 more
semanticscholar   +1 more source

Lecithinized SOD for a clinically applicable SOD preparation.

Drug Delivery System, 1995
Superoxide dismutase (SOD), an enzyme that scavenges superoxide anion (O2-), has been suggested as a possible therapeutic tool, for treating diseases related to active oxygen spiecies. However, its low cell membrane affinity and rapid metabolic clearance limit its clinical application.
openaire   +3 more sources