Results 51 to 60 of about 165,528 (260)

Engineered Au@CeO2 Hybrid Nanoparticles With Microenvironment Dependent Self‐Adjustability for Integration of Tumor‐Specific Photothermal‐Chemodynamic Therapy and Inflammation Prevention

Advanced Science, EarlyView.
An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu, Wenjuan Tang, Handan Zhang, Jie Liu, Jiaqi Zhang, Yu Yao, Xiao Fu, Xin Chen, Yanmin Zhang   +8 more
wiley   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

Advanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang, Wei Tong, Qiong Wu, Didi Wu, Yanrui Zhang, Qijuan Gao, Fangdong Li, Zhaoliang Zhang, Wenjie Wang, Chuankui Song, Enhua Xia   +10 more
wiley   +1 more source

Protective Effects of Different Doses of Pycnogenol Extract against Gamma Radiation-induced Liver Damage in Rat

Erciyes Medical Journal, 2020
Objective: The study aims to investigate the protective role of pycnogenol extract against liver damage in whole-body gamma-irradiated rats by assessing DNA damage, histopathological changes and biochemical parameters.
Fazile Cantürk Tan, Arzu Hanım Yay, Oğuz Galip Yıldız, Yusuf Caner   +3 more
doaj   +1 more source

Differential Expression of EC‐SOD, Mn‐SOD and CuZn‐SOD in Rat Lung Exposed to Crystalline Silica

Journal of Occupational Health, 2007
Differential Expression of EC‐SOD, Mn‐SOD and CuZn‐SOD in Rat Lung Exposed to Crystalline Silica: Heungnam Kim, et al. Cell and Cancer Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, USA—Superoxide dismutases (SODs) are antioxidant enzymes that catalyze the dismutation of superoxide into hydrogen ...
Kim, Heungnam, Morimoto, Yasuo, Ogami, Akira, Nagatomo, Hiroko, Hirohashi, Masami, Oyabu, Takako, Kawanami, Yukiko, Kuroda, Etsushi, Higashi, Toshiaki, Tanaka, Isamu   +9 more
openaire   +3 more sources

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Lecithinized SOD for a clinically applicable SOD preparation.

Drug Delivery System, 1995
Superoxide dismutase (SOD), an enzyme that scavenges superoxide anion (O2-), has been suggested as a possible therapeutic tool, for treating diseases related to active oxygen spiecies. However, its low cell membrane affinity and rapid metabolic clearance limit its clinical application.
openaire   +3 more sources

History of pain theories (Storie delle teorie del dolore)

Pathos, 2013
The history of pain is as long as that of the human race. Several theories have been developed but none of them are yet exhaustive. Historically, the clinical approach has reflected the vision that society had about pain.
Mirko Silvestrini, Claudio A. Caputi
doaj  

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source

Mechanism of TangGanJian on nonalcoholic fatty liver disease with type 2 diabetes mellitus

Pharmaceutical Biology, 2018
Context: TangGanJian (TGJ) has a curative effect in the clinical treatment of nonalcoholic fatty liver disease (NAFLD) with type 2 diabetes mellitus (T2DM), while the mechanism involved in the treatment process remains unclear.
Yanbo Fan, Wei Xiong, Jingjing Li, Aimin Hu, Zhiwei He, Jiawen Zhang, Guoyun Zhou, Qiang Yin   +7 more
doaj   +1 more source

Assessing the hepatoprotective efficacy of Vitis gracilis Wall. against doxorubicin-induced hepatic injury in rats [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Doxorubicin is an anticancer drug that can adversely affect the liver. Therefore, seeking medical attention to manage pain and minimize side effects is crucial.
Yurnadi Hanafi Midoen, Syafruddin Ilyas, Putra Santoso   +2 more
doaj   +1 more source