Results 141 to 150 of about 72,561 (329)
Molecular Lysine Tweezers Counteract Aberrant Protein Aggregation. [PDF]
, 2019 Molecular tweezers (MTs) are supramolecular host molecules equipped with two aromatic pincers linked together by a spacer (Gakh, 2018). They are endowed with fascinating properties originating from their ability to hold guests between their aromatic ...
Bitan, Gal +4 more
core
Вавиловский журнал генетики и селекции, 2015 Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, which affects motor neurons in the brain and spinal cord and leads to patients’ death.
N. A. Alemasov +2 more
doaj
Frontiers in Molecular Biosciences, 2016 Dominant mutations in Cu/Zn-superoxide dismutase (SOD1) gene have been shown to cause a familial form of amyotrophic lateral sclerosis (SOD1-ALS). A major pathological hallmark of this disease is abnormal accumulation of mutant SOD1 oligomers in the ...
Itsuki Anzai +7 more
doaj +1 more source
Effects of Carbon Dioxide, Oxygen, and Ethylene Levels of Kentucky Bluegrass Sod1 [PDF]
, 1982 J. W. King, J. B. Beard, P. E. Rieke
openalex +1 more source
Food Frontiers, EarlyView.Our results indicate that maternal ISO‐S during late gestation and throughout lactation can improve offspring intestinal homeostasis, which may be related to antioxidant enzymes and immunoglobulins in sow colostrum through maternal metabolome–microbiome intestine interactions.
Changming Hong +9 more
wiley +1 more source
Overexpression of human copper,zinc-superoxide dismutase (SOD1) prevents postischemic injury [PDF]
, 1998 Penghai Wang +6 more
openalex +1 more source
Glia, EarlyView.Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao +9 more
wiley +1 more source
Neurobiology of Disease, 2006 Amyotrophic lateral sclerosis (ALS) is a fatal disease of unknown etiology. Mutations in copper/zinc superoxide dismutase (SOD1) are the most commonly associated genetic abnormality. Given that SOD1 is ubiquitously expressed, the exclusive vulnerability of motor neurons is one of the most puzzling issues in ALS research.
Teresa Sanelli +7 more
openaire +4 more sources
Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1 [PDF]
, 1998 Jiming Kong, Zuoshang Xu
openalex +1 more source
Glia, EarlyView.TDP‐43Q331K mice exhibit altered proliferative dynamics in oligodendrocytes and their precursors. Oligodendroglial cell death is evident in TDP‐43Q331K mice. TDP‐43Q331K mice display altered myelin reflectance and pathology in the spinal cord. ABSTRACT Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the ...
Katherine N. Lewis +8 more
wiley +1 more source