Results 151 to 160 of about 74,541 (281)
A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS [PDF]
, 2015 Seiichi Nagano +6 more
openalex +1 more source
Linking Superoxide Production and Scavenging in Plant Development
Plant, Cell &Environment, EarlyView.ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák +3 more
wiley +1 more source
Individual Oligogenic Background in p.D91A-SOD1 Amyotrophic Lateral Sclerosis Patients [PDF]
, 2021 Giulia Gentile +6 more
openalex +1 more source
Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review
Photochemistry and Photobiology, EarlyView.Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima +6 more
wiley +1 more source
Aberrant Methylation of the SOD1 GENE, its Expression and Enzyme Activity in the Placenta of Patients with Preeclampsia. [PDF]
, 2023 Saba Zakeri +5 more
openalex +1 more source
Experimental Physiology, EarlyView.Abstract Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). Early research framed ROS as deleterious byproducts of exercise, but subsequent studies have established their roles as signalling molecules involved in mitochondrial biogenesis,
Malcolm J. Jackson
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Heart failure (HF) with a mildly reduced ejection fraction (HFmrEF; 40%–49%) is present in ≤25% of HF patients. Therapeutic treatment options for HFmrEF‐associated exercise intolerance are limited. Nitric oxide (NO)‐independent stimulation of soluble guanylyl cyclase to improve peripheral vasodilatation offers a novel approach to enhance ...
Ramona E. Weber +10 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Hyperthermia has recently been applied to treat human non‐small cell lung cancer (NSCLC). However, the mechanisms underlying cytotoxic sensitivity of NSCLC cells to hyperthermia are not fully understood. In this study, five NSCLC cell lines with different epidermal growth factor receptor (EGFR), Kirsten rat sarcoma and tumor protein p53 ...
Yun‐Chieh Tu +10 more
wiley +1 more source