Results 181 to 190 of about 72,561 (329)

Accumulation of dysfunctional SOD1 protein in Parkinson’s disease is not associated with mutations in the SOD1 gene [PDF]

Acta Neuropathologica, 2017
Glenda M. Halliday, Benjamin G. Trist, Jennifer A. Fifita, Kay L. Double, Dominic J. Hare, Dominic J. Hare, Dominic J. Hare, Simon J.G. Lewis, Simon J.G. Lewis, Sarah E. Freckleton, Ian P. Blair   +10 more
openaire   +2 more sources

Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS [PDF]

, 2005
Martin R. Turner, Abena Osei‐Lah, Alexander Hammers, Ammar Al‐Chalabi, Christopher E. Shaw, Peter M. Andersen, David J. Brooks, P. Nigel Leigh, Kerry Mills   +8 more
openalex   +1 more source

TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models

The FEBS Journal, EarlyView.
The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir, Joerg Buddenkotte, Majid Ali Alam, Ahmed Own, Randall J. Eck, Brian C. Kraemer, Eckhard Mandelkow, Martin Steinhoff   +7 more
wiley   +1 more source

Protein production is an early biomarker for RNA‐targeted therapies [PDF]

, 2018
Alex, Jacob, Barthélemy, Nicolas, Bateman, Randall J, Bollinger, James G, Cole, Tracy, Kordasiewicz, Holly B, Miller, Timothy M, Sato, Chihiro, Schoch, Kathleen M, Self, Wade K, Swayze, Eric   +10 more
core   +2 more sources

DNA damage in mitosis: SOD1 delays anaphase onset

The FEBS Journal, EarlyView.
Mitotic cells do not exhibit a DNA damage checkpoint delay and do not repair DNA double strand breaks (DSBs) until the next cell cycle. Instead, DSBs can delay anaphase through the mitotic spindle checkpoint, by an incompletely understood mechanism. Li et al.
George Zachos
wiley   +1 more source

Copper, Ceruloplasmin and Superoxide Dismutase (SOD1) in Patients with Down's Syndrome

, 2001
Gudlaug Tórsdóttir, Jakob Kristinsson, Stefán Hreiðarsson, Jón Snædal, Torkell Jøhannesson   +4 more
openalex   +1 more source

SOD1 overexpression alters ROS production and reduces neurotoxic inflammatory signaling in microglial cells [PDF]

, 2006
Filomena O. Dimayuga, Chunmei Wang, Jordan M. Clark, Edgardo Dimayuga, Vanessa M. Dimayuga, Annadora J. Bruce‐Keller   +5 more
openalex   +1 more source

Effects of an Isoquinoline Alkaloids Blend on the Expression of Genes Relevant for Antioxidant Capacity, Barrier Integrity and Inflammation Along the Broiler Gut

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Intensive broiler production may lead to perturbations of gut function and health. The maintenance of intestinal homeostasis in broilers through the use of dietary phytogenic components such as isoquinoline alkaloids (IQs) is an emerging topic of scientific investigations.
Vasileios V. Paraskeuas, Ioannis Brouklogiannis, Anja Pastor, Konstantinos C. Mountzouris   +3 more
wiley   +1 more source

Diagnosis of degenerative myelopathy in a Boston terrier–French bulldog mixed breed

Journal of Small Animal Practice, EarlyView.
Canine degenerative myelopathy (DM) has been associated with mutations in the superoxide dismutase 1 gene (SOD1). Although the SOD1:c.118G>A mutation has been identified in Boston terriers and French bulldogs, no histological‐confirmed degenerative myelopathy has been reported in either breed.
A. M. K. Chan, J. R. Coates, G. C. Johnson, H. N. Snyman, D. W. Silversides   +4 more
wiley   +1 more source

SESSION 7A Interpretation of Data from SOD1 Models [PDF]

, 2006

openalex   +1 more source