Results 211 to 220 of about 72,561 (329)

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source

Distinct amyloid fibril structures formed by ALS-causing SOD1 mutants G93A and D101N. [PDF]

EMBO Rep
Zhang MY, Ma Y, Wang LQ, Xia W, Li XN, Zhao K, Chen J, Li D, Zou L, Wang Z, Liu C, Liang Y.   +11 more
europepmc   +1 more source

Mutant SOD1^G93A microglia are more neurotoxic relative to wild‐type microglia [PDF]

, 2007
Qin Xiao, Weihua Zhao, David R. Beers, Albert Yen, Wenjie Xie, Jenny S. Henkel, Stanley H. Appel   +6 more
openalex   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

The Significance and Mechanism of Cerebral Enlarged Perivascular Space in Amyotrophic Lateral Sclerosis. [PDF]

Int J Mol Sci
Lee BC, Kuo YC, Cheng LF, Tsai YC, Huang JZ, Tsai HH, Lin JS, Huang PY, Ting CH, Yang CC, Lai HJ, Chao CC, Tsai LK.   +12 more
europepmc   +1 more source

Angiotensin‐converting enzyme 2 regulates the placental response to repeated hypoxia–reoxygenation insult

The Journal of Physiology, EarlyView.
Abstract figure legend Term placental explants (n = 8 per group) were cultured for 24 h in normoxia (8% O2), non‐physiological hypoxia–reoxygenation [H/R; 6 h cycles of 1% (hypoxia chamber) and 8% O2 (incubator)] or a novel physiological H/R model (6 h cycles of 1% and 8% O2 in a single hypoxia chamber), with or without recombinant human angiotensin ...
India A. Brooker, Jessie M. Sutherland, Saije K. Endacott, Eugenie R. Lumbers, Joshua J. Fisher, Kirsty G. Pringle   +5 more
wiley   +1 more source

<i>SOD1</i> and <i>CAT</i> gene expressions in stray and owned animals. [PDF]

Vet Med (Praha)
Sonmez G, Temizkan MC, Culha MH.
europepmc   +1 more source

Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: A model of age-related macular degeneration

, 2006
Yutaka Imamura, Setsuko Noda, Kouhei Hashizume, Kei Shinoda, Mineko Yamaguchi, Satoshi Uchiyama, Takahiko Shimizu, Yutaka Mizushima, Takuji Shirasawa, Kazuo Tsubota   +9 more
openalex   +1 more source

Understanding the impact of glycolysis and oxidative stress on residual feed intake in slow-growing chicken. [PDF]

Poult Sci
Niyomphong R, Kaewsatuan P, Pengsanthia S, Molee W, Molee A.   +4 more
europepmc   +1 more source

Human CAR Tregs Targeting SOD1 and Expressing BDNF Reduce Inflammation and Delay Disease in G93A hSOD1-NSG Mice. [PDF]

Cells
Graber DJ, Cook WJ, Sentman ML, Murad-Mabaera JM, Stommel EW, Sentman CL.   +5 more
europepmc   +1 more source