Results 211 to 220 of about 74,541 (281)

Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice

, 2009
Christian S. Lobsiger, Séverine Boillée, Melissa McAlonis‐Downes, Amir M. Khan, M. Laura Feltri, Koji Yamanaka, Don W. Cleveland   +6 more
openalex   +2 more sources

Unveiling the Genetic Association Between Hemoglobin Concentration and Amyotrophic Lateral Sclerosis

Brain and Behavior, Volume 16, Issue 1, January 2026.
This study identified a causal relationship between genetically predicted hemoglobin (Hb) concentration and amyotrophic lateral sclerosis (ALS) through Mendelian randomization (MR), and integrated RNA‐seq and RT‐qPCR analyses to highlight BACH1, FLVCR1, and TRIM58 as potential genes involved in this association.
Hongmei Luo, Yujie Yang, Xiaojian Cao, Chunchu Deng, Hong Chen   +4 more
wiley   +1 more source

Nerve Root Enhancement and Elevated Cerebrospinal Fluid Protein in Four Patients With SOD1-Linked Amyotrophic Lateral Sclerosis. [PDF]

Eur J Neurol
Vacchiano V, Ragucci C, Rizzo G, Di Stasi V, Pastorelli F, Rinaldi R, Provini F, Postiglione E, Fiorentino A, Carelli V, Liguori R.   +10 more
europepmc   +1 more source

Melatonin‐engineered MSCs‐exosomes deliver USP4 to stabilise ARNTL and inhibit clock rhythmic ferroptosis for enhanced flap survival

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
• Sleep restriction induces clock rhythmic ferroptosis, leading to skin flap necrosis. • MEXOs deliver USP4 to stabilise ARNTL, restoring circadian rhythm and inhibiting ferroptosis. • The METTL3/YTHDF1 m6A axis up‐regulates USP4 in melatonin‐preconditioned BMSCs.
Xiaoqiong Jiang, Yu Wang, Xuanlong Zhang, Huiming Deng, Liangyu Fang, Chaire Tafadzwa, Jiangnan Yao, Hao Chen, Anqi Ye, Kailiang Zhou, Xiangwei Ling, Jian Xiao   +11 more
wiley   +1 more source

The protective role of dietary nutrients in mitigating asthma risks induced by indoor air pollutants: a comparative toxicogenomics perspective. [PDF]

Sci Rep
Sun Z, Yang Y, Lin D, Liu Y, Su Y, Wang B.   +5 more
europepmc   +1 more source

Altered Inflammatory Signature in a C9ORF72 ‐ALS iPSC‐Derived Motor Neuron and Microglia Coculture Model

Glia, Volume 74, Issue 1, January 2026.
Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao, Jessica L. Brothwood, Harpreet Saini, Gregory A. O'Sullivan, Carla F. Bento, James M. McCarthy, Nicola G. Wallis, Elena Di Daniel, Brent Graham, Daniel M. Tams   +9 more
wiley   +1 more source

Enzyme Immobilization in Porous Crystals via Cage Encapsulation. [PDF]

Angew Chem Int Ed Engl
Liu HK, Nakama T, Funami S, Ebihara R, Mitsuhashi T, Fujita M.   +5 more
europepmc   +1 more source

Postmitotic Expression of SOD1^G93A Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation [PDF]

, 2015
Martina Martini, Gabriella Dobrowolny, Michela Aucello, Antonio Musarò   +3 more
openalex   +1 more source

Oligodendroglial Densities and Myelin Structure Are Altered in TDP‐43 Related Amyotrophic Lateral Sclerosis

Glia, Volume 74, Issue 1, January 2026.
TDP‐43Q331K mice exhibit altered proliferative dynamics in oligodendrocytes and their precursors. Oligodendroglial cell death is evident in TDP‐43Q331K mice. TDP‐43Q331K mice display altered myelin reflectance and pathology in the spinal cord. ABSTRACT Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the ...
Katherine N. Lewis, Georgina A. Craig, Joel Mason, Doris Tomas, Brittany Cuic, Adam K. Walker, David G. Gonsalvez, Bradley J. Turner, Samantha K. Barton   +8 more
wiley   +1 more source

Clove Essential Oil Enhances Antioxidant Defenses and Reduces DNA Damage in a Cellular Model of Parkinson's Disease. [PDF]

Parkinsons Dis
Hamdi D, Ouachik O, Kocer A, Ouchchane L, Messaoud C, Hafidi A.   +5 more
europepmc   +1 more source