Results 261 to 270 of about 72,561 (329)

Rethinking ALS: Current understanding and emerging therapeutic strategies. [PDF]

AIMS Neurosci
Arachchige ASPM.
europepmc   +1 more source

Health Benefits and Food Applications of Bioactive Constituents From Different Medicinal Parts (Bark, Leaf, and Fruit) of Lycium barbarum

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
The bioactive ingredients, pharmacological effects, food applications, and safety of Lycium barbarum. ABSTRACT Lycium barbarum is a plant that is a member of the Solanaceae family. Different tissues and organs from this plant are widely used in traditional Chinese medicine because of their abundant functional ingredients.
Mengfan Peng, Caixia Li, Xue Yang, Tingting Ye, Baosong Liu   +4 more
wiley   +1 more source

OPTN deficiency through CRISPR/Cas9 downregulates autophagy and mitophagy in a SOD1-G93A-expressing transgenic cell line. [PDF]

IBRO Neurosci Rep
Wen D, Li Q, Li Y, Yan W, Wang Y, Liu Y.
europepmc   +1 more source

The Values and Preferences of People Living With Motor Neurone Disease (MND): A Systematic Review Protocol

Clinical and Public Health Guidelines, Volume 2, Issue 4, October 2025.
ABSTRACT Objective To systematically review the values and preferences of people with lived experience of motor neurone disease (MND), including those living with MND, caregivers and genetic carriers, regarding their health‐related outcomes. Introduction MND is a devastating neurodegenerative disease that significantly impacts those living with the ...
Timothy Hugh Barker, Grace Holland, Camille Schubert, Danielle Pollock, Cindy Stern, Nipun Shrestha, Wojtek Wiercioch, Samer Karam, Steve Vucic, Jay Beasley‐Hall, Lynne Giles, Tracy Merlin, Zachary Munn   +12 more
wiley   +1 more source

Phenotypic Characterization of ALS-Causing SOD1 Mutations Affecting Polypeptide Length. [PDF]

Hum Mutat
Berdyński M, Safranow K, Andersen PM, Żekanowski C.   +3 more
europepmc   +1 more source

Mechanisms of Osteoblast‐Like Cells and Bacterial Responses to Copper in Titanium‐Copper Alloys

Journal of Biomedical Materials Research Part A, Volume 113, Issue 10, October 2025.
ABSTRACT Titanium‐copper (Ti‐Cu) alloys are gaining attention for their dual functionality in promoting osteogenesis while providing antimicrobial protection, making them ideal candidates for dental and orthopedic implants. Copper's ability to enhance bone cell activity and inhibit bacterial growth could help address two critical challenges: successful
Javeria Khalid, Abish S. Stephen, Simon C. F. Rawlinson, Robert P. Allaker   +3 more
wiley   +1 more source

Copper supplementation mitigates Parkinson-like wild-type SOD1 pathology and nigrostriatal degeneration in a novel mouse model. [PDF]

Acta Neuropathol Commun
Rowlands BD, Trist BG, Karozis C, Schaffer G, Mor D, Harwood R, Rosolen SA, Cottam V, Persson-Carboni F, Richardson M, Li AA, Gotsbacher MP, Abdeen AH, Codd R, Double KL.   +14 more
europepmc   +1 more source

Targeting oxidized phosphatidylcholines in SOD1-associated ALS: therapeutic potential of PC-OxPL-VecTab^®. [PDF]

Front Neurosci
Gomes-Duarte A, Pascoal S, Haselberg R, Sogorb-Gonzalez M, van Deventer S.   +4 more
europepmc   +1 more source

Telomere‐Related Gene Networks in the Ovary Shift Across Environmental Factors

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 343, Issue 8, Page 893-904, October 2025.
ABSTRACT The ovary is key to linking environmental factors with the timing and quality of offspring development. Focused on free‐living female tree swallows (Tachycineta bicolor), we measured temporal variation in ovarian expression of genes involved in the regulation of telomere length.
Sarah E. Wolf, Elizabeth M. George, Jess Dong, Kimberly A. Rosvall   +3 more
wiley   +1 more source

SOD1 Protein Content in Human Central Nervous System and Peripheral Tissues. [PDF]

J Neurochem
Leykam L, Jonsson PA, Forsberg KME, Andersen PM, Brännström T, Marklund SL, Zetterström P.   +6 more
europepmc   +1 more source