Results 261 to 270 of about 74,541 (281)

Aspergillus fumigatus copper export machinery and reactive oxygen intermediate defense counter host copper-mediated oxidative antimicrobial offense [PDF]

, 2017
Dinauer, Mary C, et al,, Idol, Rachel A
core   +1 more source

Edible and Medicinal Fritillaria thunbergii Miq. Aqueous Extract Improves Metabolic Health via Modulation of Gut Microbiota in Mice Fed on a High‐Sugar and High‐Fat Diet

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Fritillaria thunbergii Miq. (FTM), a traditional medicinal and edible herb, has shown promise in alleviating metabolic disturbances, yet its mechanistic basis remains unclear. In this study, we investigated the therapeutic effects of FTM aqueous extract in a male KM mouse model of obesity induced by a high‐sugar, high‐fat diet (HSFD).
Linen Zou, Yu Fu, Lanna Wu, Jiale Cheng, Yanan Yang, Mingxi Li, Yuru Xu, Yan Jiang, Qingchun Wang, Chongming Wu, Hongxun Tao   +10 more
wiley   +1 more source

Morpholino-RNA duplex exhibits robust, sustained, and safe steric-block antisense activity by intracerebroventricular and intrathecal injection. [PDF]

Nat Commun
Yanagidaira M, Nagata T, Hasegawa J, Ishii T, Ebihara S, Nawa M, Yokota T.   +6 more
europepmc   +1 more source

Renalase deficiency suppresses hepatic triglyceride accumulation in the progression to MASLD/MASH by GAN diet in male mice

Physiological Reports, Volume 14, Issue 2, January 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a growing public health concern characterized by hepatic triglyceride (TG) accumulation, inflammation, and fibrosis. Renalase is known for its role in blood pressure regulation and catecholamine metabolism, but recent evidence suggests broader cytokine‐like functions. Moreover,
Yota Okano, Katsuyuki Tokinoya, Kai Aoki, Yuri Kato, Yasushi Kawakami, Kazuhiro Takekoshi   +5 more
wiley   +1 more source

Correction to "TSPO Expression and [18F]DPA-714 PET/CT Imaging as Pathogenetic and Diagnostic Biomarkers in Symptomatic Stages of Skeletal Muscle Fiber Degeneration in SOD1-G93A ALS Mice". [PDF]

FASEB J
europepmc   +1 more source

Antisense Oligonucleotide Therapy for Amyotrophic Lateral Sclerosis (ALS): An Umbrella Review. [PDF]

Cureus
Jeong E, Li D.
europepmc   +1 more source

Inducible Ift88‐deficient mice show features consistent with mild pulmonary hypertension

Physiological Reports, Volume 14, Issue 2, January 2026.
Abstract Intraflagellar transport protein 88 (IFT88) is essential for primary and motile cilia formation. In murine models and humans, Ift88 mutations contribute to renal cysts, epithelial proliferation and impaired immune responses. In mice, Ift88 knockout (KO) reduces airway cilia, increases airway epithelial proliferation and hyperreactivity ...
Selina M. Garcia, Benjamin J. Lantz, Helen J. Wagner, David T. Jones, Rene Arechiga‐Gonzalez, Tamara A. Howard, Sana Gul, Terry H. Wu, Thomas F. Byrd, Olivia C. Heath, Laura V. Gonzalez Bosc   +10 more
wiley   +1 more source

Understanding Keratoconus in Down Syndrome: From Etiology to Management - A Narrative Review. [PDF]

Clin Ophthalmol
Anitha V, Nallasamy N, Christy JS, Kristianslund O, Stephenson KAJ, Hashemi H, Rajaraman R, Asgari S.   +7 more
europepmc   +1 more source

Surrogate Endpoints in Regulatory Decision-Making. [PDF]

Clin Transl Sci
Jeng LJB, Siegel J.
europepmc   +1 more source

Distinct amyloid fibril structures formed by ALS-causing SOD1 mutants G93A and D101N. [PDF]

EMBO Rep
Zhang MY, Ma Y, Wang LQ, Xia W, Li XN, Zhao K, Chen J, Li D, Zou L, Wang Z, Liu C, Liang Y.   +11 more
europepmc   +1 more source