Results 281 to 290 of about 72,561 (329)

Superoxide Activates Ferroptosis via the Haber‐Weiss Reaction and Enhances Age‐Related Macular Degeneration

Aging Cell, Volume 24, Issue 10, October 2025.
Superoxide activates ferroptosis through the Haber‐Weiss reaction and contributes to the development of age‐related macular degeneration. MnSOD‐depleted RPE cells are susceptible to blue light‐induced ferroptosis. MnSOD deficiency promotes Hsp70‐driven ubiquitin‐mediated degradation of GPX4.
Ying Huang, Zhenxing Zhou, Mengjia Huan, Qi Guo, Xiaoqian Zhang, Ruiqi Lu, Lushu Chen, Xiumiao Li, Jin Yao, Qin Jiang, Yong Xu   +10 more
wiley   +1 more source

Programmable self-replicating JEV nanotherapeutics redefine RNA delivery in ALS. [PDF]

Commun Biol
Loo YS, Yusoh NA, Yap K, Ng CS.
europepmc   +1 more source

2025 ACVIM Forum Research Abstract Program

Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
wiley   +1 more source

Survey of functional Mendelian variants in New Zealand Huntaway and Heading dog breeds

Animal Genetics, Volume 56, Issue 5, October 2025.
Abstract New Zealand (NZ) Huntaway and Heading dogs are working breeds that play active roles on farms across NZ. While these breeds are common in NZ, they are not well‐known elsewhere, and little is understood about their genetic make‐up. Here, we used whole genome sequencing to provide a comprehensive genomic view of 249 working dogs. As first use of
Florence Smith, Thomas Lopdell, Melissa Stephen, Millicent Henry, Keren Dittmer, Hayley Hunt, Nick Sneddon, Liam Williams, Jack Rolfe, Dorian Garrick, Mathew D. Littlejohn   +10 more
wiley   +1 more source

Beyond Antioxidants: How Redox Pathways Shape Cellular Signaling and Disease Outcomes. [PDF]

Antioxidants (Basel)
Alhaj Sulaiman A, Katanaev VL.
europepmc   +1 more source

Aspergillus fumigatus copper export machinery and reactive oxygen intermediate defense counter host copper-mediated oxidative antimicrobial offense [PDF]

, 2017
Dinauer, Mary C, et al,, Idol, Rachel A
core   +1 more source

Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases

British Journal of Pharmacology, Volume 182, Issue 19, Page 4466-4489, October 2025.
Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota, Theodora Calogeropoulou, Konstantina Chanoumidou, Ioannis Charalampopoulos, Achille Gravanis   +4 more
wiley   +1 more source

Artesunate improves cryopreserved yak sperm quality by activating SOD1 antioxidant pathway. [PDF]

Front Vet Sci
Fan Y, Lv W, Li X, Wanma G, Li J, Xiong X, He X, Wang Y, Yin S, Fu W, He H, Lin Y, Lan D, Xiong Y.   +13 more
europepmc   +1 more source