Results 171 to 180 of about 23,359 (316)

Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: results of the CABG surgery cohort of the GUARDIAN study [PDF]

, 2003
Steven W. Boyce, Claus Bartels, Roberto Bolli, Bernard Chaitman, John C. Chen, Eric Chi, Andreas Jessel, Dean J. Kereiakes, John Knight, L Thulin, Pierre Théroux   +10 more
openalex   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Structure and Inhibition of the Human Na⁺/H⁺ Exchanger SLC9B2. [PDF]

Int J Mol Sci
Jung S, Kokane S, Li H, Iwata S, Nomura N, Drew D.   +5 more
europepmc   +1 more source

Aminoimidazoles as bioisosteres of acylguanidines: novel, potent, selective and orally bioavailable inhibitors of the sodium hydrogen exchanger isoform-1

, 2003
Saleem Ahmad, Khehyong Ngu, Donald W. Combs, Shung Wu, David S. Weinstein, Wen Liu, Bang‐Chi Chen, Gamini Chandrasena, Charles R. Dorso, Mark Kirby, Karnail S. Atwal   +10 more
openalex   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Mechanism of reduced intestinal phosphate absorption by tenapanor: a hypothesis. [PDF]

Clin Kidney J
Nakanishi T, Drueke TB, Kuragano T.
europepmc   +1 more source

Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3

, 2004
Shaoying Li, Soichiro Sato, Xiaojing Yang, Patricia A. Preisig, Robert J. Alpern   +4 more
openalex   +2 more sources

Cation-exchange mediated synthesis of hydrogen and sodium titanates heterojunction: Theoretical and experimental insights toward photocatalyic mechanism

, 2020
Isabela M. Iani, Vinícius Teodoro, Naiara L. Marana, Ubirajara Coleto, Júlio R. Sambrano, A.Z. Simões, M. D. Teodoro, E. Longo, Leinig Antônio Perazolli, Rafael Aparecido Ciola Amoresi, M.A. Zaghete   +10 more
openalex   +2 more sources

Cell Confluence-induced Activation of Signal Transducer and Activator of Transcription-3 (Stat3) Triggers Epithelial Dome Formation via Augmentation of Sodium Hydrogen Exchanger-3 (NHE3) Expression [PDF]

, 2007
Hsiao-Wen Su, Hsuan-Heng Yeh, Shainn-Wei Wang, Meng Shen, Tsu-Ling Chen, Pawel R. Kiela, Fayez K. Ghishan, Ming‐Jer Tang   +7 more
openalex   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

Advanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan, Keshav Gajendra Babu, Markus Mukenhirn, Antje Garside, Vinita Ajit Kini, Trishla Adhikari, Timon Beck, Byung Ho Lee, Kyoohyun Kim, Carsten Werner, Raimund Schlüßler, Alf Honigmann, Sebastian Aland, Anna Verena Taubenberger   +13 more
wiley   +1 more source