Results 91 to 100 of about 22,819 (283)

Anoctamin 1 is Apically Expressed on Thyroid Follicular Cells and Contributes to ATP- and Calcium-Activated Iodide Efflux

open access: yesCellular Physiology and Biochemistry, 2014
Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating this transport have only been partially identified.
Carmela Iosco   +10 more
doaj   +1 more source

Evaluating the Natrium Iodide Symporter Expressions in Thyroid Tumors [PDF]

open access: yes, 2021
BACKGROUND: Decreased Natrium iodide symporter (NIS) expression levels or diminished NIS targeting thyroid cancer cells’ plasma membrane leads to radioiodine-refractory disease.
Elliyanti, Aisyah   +4 more
core   +2 more sources

Differentiated thyroid cancer: Growth factors, oncogenes and environmental influences [PDF]

open access: yesArchive of Oncology, 2003
The present data of growth factors, oncogenes, tumor-suppressor-genes and environmental factors can be summarized in thus: thyrotropin, growth factors and other hormones do increase thyrocyte growth and specific mutations of growth factor receptors ...
Paunović Ivan R.
doaj   +1 more source

Translational Research Using Sodium/Iodide Symporter

open access: yesJournal of Korean Endocrine Society, 2006
184 1915년에 갑상선 조직에 요오드가 선택적으로 축적된다 는 사실이 밝혀졌고, 그 이후 갑상선 질환의 진단과 치료에 방사성요오드가 널리 이용되게 되었다. 갑상선 조직은 요오 드를 혈액에서부터 20~40배 정도 높은 농도로 축적한다. 약 60년 전부터 방사성요오드를 갑상선 기능을 측정하는 추적 자로 사용하였고, 곧이어 갑상선기능항진증과 갑상선암에서 I-131를 치료제로 사용하게 되었다. 그러나 갑상선 세포에 요오드가 선택적으로 섭취되는 기 전은 최근에야 밝혀졌다.
Joo Hyun Kang, June-Key Chung
openaire   +2 more sources

Perchlorate, nitrate, and thiocyanate: Environmental relevant NIS-inhibitors pollutants and their impact on thyroid function and human health

open access: yesFrontiers in Endocrinology, 2022
Thyroid disruptors are found in food, atmosphere, soil, and water. These contaminants interfere with the thyroid function through the impairment of thyroid hormone synthesis, plasma transport, peripheral metabolism, transport into the target cells, and ...
Caroline Serrano-Nascimento   +2 more
doaj   +1 more source

Measles to the Rescue: A Review of Oncolytic Measles Virus [PDF]

open access: yes, 2016
Oncolytic virotherapeutic agents are likely to become serious contenders in cancer treatment. The vaccine strain of measles virus is an agent with an impressive range of oncolytic activity in pre-clinical trials with increasing evidence of safety and ...
Aref, S, Bailey, K, Fielding, A
core   +2 more sources

Recent Advances in Cancer Cell Membrane‐Based Nanoparticles and Cancer Cell‐Derived Small Extracellular Vesicles as Drug Delivery Platforms

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 6, June 2025.
Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang   +4 more
wiley   +1 more source

Treatment of medulloblastoma using an oncolytic measles virus encoding the thyroidal sodium iodide symporter shows enhanced efficacy with radioiodine

open access: yesBMC Cancer, 2012
Background Medulloblastoma is the most common malignant brain tumor of childhood. Although the clinical outcome for medulloblastoma patients has improved significantly, children afflicted with the disease frequently suffer from debilitating side effects ...
Hutzen Brian   +5 more
doaj   +1 more source

Anti-thyroid antibodies: methodological aspects and diagnostic significance [PDF]

open access: yes, 2003
Since the first publication, more than 40 years ago, laboratory tests for the presence of antibodies (Ab) to thyroid antigens (Ag) have played a pivotal position in the diagnosis of thyroid diseases.
Hauache, Omar M.   +3 more
core   +3 more sources

Size Increment During Surveillance in Papillary Thyroid Cancer: Evidence Synthesis and Dose–Response Meta‐Analysis

open access: yesCancer Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Introduction Differentiated thyroid cancer has become a prevalent malignant tumor, particularly papillary thyroid carcinoma (PTC), constituting over 90% of cases. Most PTC lesions are asymptomatic and remain subclinical throughout life, and active surveillance is now being used to monitor the progression of these lesions and intervene when ...
Mohamed Badie Ahmed   +8 more
wiley   +1 more source

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