Results 91 to 100 of about 22,963 (277)

Translational Research Using Sodium/Iodide Symporter

open access: yesJournal of Korean Endocrine Society, 2006
184 1915년에 갑상선 조직에 요오드가 선택적으로 축적된다 는 사실이 밝혀졌고, 그 이후 갑상선 질환의 진단과 치료에 방사성요오드가 널리 이용되게 되었다. 갑상선 조직은 요오 드를 혈액에서부터 20~40배 정도 높은 농도로 축적한다. 약 60년 전부터 방사성요오드를 갑상선 기능을 측정하는 추적 자로 사용하였고, 곧이어 갑상선기능항진증과 갑상선암에서 I-131를 치료제로 사용하게 되었다. 그러나 갑상선 세포에 요오드가 선택적으로 섭취되는 기 전은 최근에야 밝혀졌다.
Joo Hyun Kang, June-Key Chung
openaire   +2 more sources

A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection

open access: yesFood Frontiers, Volume 6, Issue 4, Page 1658-1700, July 2025.
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah   +1 more
wiley   +1 more source

Differentiated thyroid cancer: Growth factors, oncogenes and environmental influences [PDF]

open access: yesArchive of Oncology, 2003
The present data of growth factors, oncogenes, tumor-suppressor-genes and environmental factors can be summarized in thus: thyrotropin, growth factors and other hormones do increase thyrocyte growth and specific mutations of growth factor receptors ...
Paunović Ivan R.
doaj   +1 more source

Perchlorate, nitrate, and thiocyanate: Environmental relevant NIS-inhibitors pollutants and their impact on thyroid function and human health

open access: yesFrontiers in Endocrinology, 2022
Thyroid disruptors are found in food, atmosphere, soil, and water. These contaminants interfere with the thyroid function through the impairment of thyroid hormone synthesis, plasma transport, peripheral metabolism, transport into the target cells, and ...
Caroline Serrano-Nascimento   +2 more
doaj   +1 more source

Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]

open access: yes, 2017
Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle   +13 more
core   +2 more sources

Updated consumer risk assessment of fluoride in food and drinking water including the contribution from other sources of oral exposure

open access: yesEFSA Journal, Volume 23, Issue 7, July 2025.
Abstract This updated risk assessment evaluated evidence on potential adverse health effects of fluoride related to all sources of oral exposure as mandated by the European Commission. Fluoride benefit assessment was not included. Effects on the central nervous system, thyroid and bone were prioritised.
EFSA Scientific Committee   +34 more
wiley   +1 more source

Treatment of medulloblastoma using an oncolytic measles virus encoding the thyroidal sodium iodide symporter shows enhanced efficacy with radioiodine

open access: yesBMC Cancer, 2012
Background Medulloblastoma is the most common malignant brain tumor of childhood. Although the clinical outcome for medulloblastoma patients has improved significantly, children afflicted with the disease frequently suffer from debilitating side effects ...
Hutzen Brian   +5 more
doaj   +1 more source

Glycosylation of Sodium/Iodide Symporter (NIS) Regulates Its Membrane Translocation and Radioiodine Uptake. [PDF]

open access: yesPLoS ONE, 2015
Human sodium/iodide symporter (hNIS) protein is a membrane glycoprotein that transports iodide ions into thyroid cells. The function of this membrane protein is closely regulated by post-translational glycosylation.
Taemoon Chung   +4 more
doaj   +1 more source

Hashimoto's thyroiditis and autoimmune gastritis [PDF]

open access: yes, 2017
The term "thyrogastric syndrome" defines the association between autoimmune thyroid disease and chronic autoimmune gastritis (CAG), and it was first described in the early 1960s.
Brusca, Nunzia   +6 more
core   +3 more sources

Reporter gene-engineering of human induced pluripotent stem cells during differentiation renders in vivo traceable hepatocyte-like cells accessible

open access: yesStem Cell Research, 2019
Primary hepatocyte transplantation (HTx) is a safe cell therapy for patients with liver disease, but wider application is circumvented by poor cell engraftment due to limitations in hepatocyte quality and transplantation strategies. Hepatocyte-like cells
Candice Ashmore-Harris   +6 more
doaj  

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