Results 101 to 110 of about 22,963 (277)

Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity

Journal of Biomedical Science, 2010
Background Sodium/iodide symporter (NIS) mediates the active transport and accumulation of iodide from the blood into the thyroid gland. His-226 located in the extracellular region of NIS has been demonstrated to be critical for iodide transport in our ...
Liang Ji-An, Wu Shih-Lu, Kao Chia-Hung, Ho Tin-Yun, Li Chia-Cheng, Hsiang Chien-Yun   +5 more
doaj   +1 more source

Recent Advances in Cancer Cell Membrane‐Based Nanoparticles and Cancer Cell‐Derived Small Extracellular Vesicles as Drug Delivery Platforms

Advanced NanoBiomed Research, Volume 5, Issue 6, June 2025.
Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang, Jingjing Wang, Long Ngo, Li Li, Yuling Wang   +4 more
wiley   +1 more source

Size Increment During Surveillance in Papillary Thyroid Cancer: Evidence Synthesis and Dose–Response Meta‐Analysis

Cancer Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Introduction Differentiated thyroid cancer has become a prevalent malignant tumor, particularly papillary thyroid carcinoma (PTC), constituting over 90% of cases. Most PTC lesions are asymptomatic and remain subclinical throughout life, and active surveillance is now being used to monitor the progression of these lesions and intervene when ...
Mohamed Badie Ahmed, Emad Naem, Harman Saman, Abeer Alsherawi, Asma Syed, Noora Al‐Abdulla, Latifa Alkaabi, Mahmoud A. Zirie, Suhail A. Doi   +8 more
wiley   +1 more source

Accomplishments and challenges in stem cell imaging in vivo. [PDF]

, 2019
Stem cell therapies have demonstrated promising preclinical results, but very few applications have reached the clinic owing to safety and efficacy concerns.
Bose, Rajendran JC, Mattrey, Robert F
core  

Measles to the Rescue: A Review of Oncolytic Measles Virus [PDF]

, 2016
Oncolytic virotherapeutic agents are likely to become serious contenders in cancer treatment. The vaccine strain of measles virus is an agent with an impressive range of oncolytic activity in pre-clinical trials with increasing evidence of safety and ...
Aref, S, Bailey, K, Fielding, A
core   +2 more sources

Preemptive iodide treatment in the event of a nuclear disaster: The prepper's guide to the galaxy

Experimental Physiology, EarlyView.
Per Karkov Cramon, Søren Holm, Ronan M. G. Berg   +2 more
wiley   +1 more source

Update of the Scientific Opinion on the risks for human health related to the presence of perchlorate in food

EFSA Journal, Volume 23, Issue 5, May 2025.
Abstract The European Commission asked EFSA to update its 2014 risk assessment on perchlorate in food. Perchlorate is a contaminant of both natural and anthropogenic sources present in food and drinking water. It is a substrate for the sodium iodide symporter (NIS) and competitively inhibits the uptake of iodide into the thyroid.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Evangelia Ntzani, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Aleksandra Buha Djordjevic, Thorhallur Halldorsson, Chantra Eskes, Olaf Mosbach‐Schulz, Francesca Riolo, Elena Rovesti, Efisio Solazzo, Alexios Zormpas, Tuuli Tauriainen, James Kevin Chipman   +27 more
wiley   +1 more source

Comparison of and as Reporter Genes for Noninvasive Imaging of Bone Mesenchymal Stem Cells Transplanted into Infarcted Rat Myocardium

Molecular Imaging, 2011
The purpose of this study was to investigate and compare the feasibility of rat sodium iodide symporter ( rNIS ) and human sodium iodide symporter ( hNIS ) as reporter genes for noninvasive monitoring of rat bone marrow mesenchymal stem cells (rBMSCs ...
Shuo Hu, Wei Cao, Xiaoli Lan, Yong He, Juntao Lang, Congjiao Li, Jia Hu, Rei An, Zairong Gao, Yongxue Zhang   +9 more
doaj   +1 more source

Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

BMC Cancer, 2002
Background Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of thyroid cancer.
Schlumberger Martin, Russo Diego, Bidart Jean-Michel, Arturi Franco, Brunetti Antonio, Chiefari Eusebio, Filetti Sebastiano   +6 more
doaj   +1 more source

Study on the Iodine 125 Uptake of H460 Lung Cancer Cell Line by Co-transfection with the Human Sodium/Iodide Symporter and the Human Thyroperoxidase [PDF]

, 2010
Background and objective Lung cancer harms people’s health or even lives severely. Especially, the therapy of non-small cell lung cancer (NSCLC) has not been obviously improved for many years.
Jian TAN, Lei LONG, Wei LI
core