Results 101 to 110 of about 10,644 (242)

Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential

The Journal of Pathology, Volume 266, Issue 4-5, Page 405-420, August 2025.
Abstract Lung cancer is the leading cause of cancer‐related death globally. To better understand the biology of lung cancer, mouse models have been developed using either tail vein‐injected tumour cell lines or genetically modified mice. The current gold‐standard models typically present with multiple lung foci.
Ana‐Rita Pedrosa, Alejandro Castillo‐Kauil, Yuliia Kravchuk, Louise Reynolds, Bruce Williams, David Moore, Cameron Lang, Srinivas Allanki, Eleni Maniati, Alexandros Hardas, Jozafina Haj, Rebecca Drake, Julie Cleaver, Julie Foster, Jana Kim, Ester Stern, Jane Sosabowski, Gilbert O. Fruhwirth, Erik Sahai, Ori Wald, Kairbaan Hodivala‐Dilke   +20 more
wiley   +1 more source

The Allele Distribution for the rs7250346 SNP in SLC5A5 among Saudis

International Journal of Medical Students, 2015
Background: The sodium/iodide cotransporter solute carrier family 5 member 5 (SLC5A5) is found in the basolateral cell membrane of thyroid follicular epithelial cells as a sodium iodide symporter.
Abdullah T. Eissa
doaj   +1 more source

Hypoxia Inhibitor Improves Iodine Uptake Disorder in Thyroid Cancer Through the hsa_circ_0023990/miR‐448/DNMT1/NIS Axis

Cancer Science, Volume 116, Issue 8, Page 2113-2124, August 2025.
Our study reveals that hypoxia inhibitors ameliorate iodine uptake dysfunction in thyroid cancer by acting on the hsa_circ_0023990/miR‐448/DNMT1/NIS signaling pathway. ABSTRACT This research seeks to investigate how hypoxia inhibitors enhance iodine uptake in thyroid cancer cells. Clinical samples were gathered and assessed for hsa_circ_0023990, DNMT1,
Ruiqin Gou, Shiqi Chen, Yangyang Lei, Pengqing Wu, Xuezhong Chen, Qing Zhang   +5 more
wiley   +1 more source

Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis

International Journal of Endocrinology, 2014
Aim. The aim of the study was to compare the expression of sodium iodide symporter (NIS), thyroglobulin (Tg), tumor necrosis factor-α (TNFα), and interleukin-1β genes in patients with Hashimoto’s thyroiditis (HT) and healthy individuals.
Anna Popławska-Kita, Beata Telejko, Katarzyna Siewko, Maria Kościuszko-Zdrodowska, Natalia Wawrusewicz-Kurylonek, Adam Krętowski, Justyna Hryniewicka, Janusz Dzięcioł, Witold Bauer, Robert Milewski, Małgorzata Szelachowska, Maria Górska   +11 more
doaj   +1 more source

Genomics‐assisted breeding for designing salinity‐smart future crops

Plant Biotechnology Journal, Volume 23, Issue 8, Page 3119-3151, August 2025.
This review explores fast‐forward genomics‐assisted breeding tools to fast‐track the designing of salinity‐smart crops. Integration of various breeding tools can enhance salinity tolerance, ensuring sustainable agriculture and global food security. Summary Climate change induces many abiotic stresses, including soil salinity, significantly challenging ...
Ali Raza, Qamar U. Zaman, Sergey Shabala, Mark Tester, Rana Munns, Zhangli Hu, Rajeev K. Varshney   +6 more
wiley   +1 more source

Untersuchungen zur transkriptionellen Regulation des Chromogranin A Gens und seine Anwendung zum zellspezifischen therapeutischen Gentransfer in neuroendokrine Pankreastumorzellen [PDF]

, 2003
Die Therapieoptionen zur Behandlung metastasierter neuroendokriner Tumore sind bisher ineffektiv. Der regulierte Gentransfer könnte eine weitere Möglichkeit eröffnen, metastasierte neuroendokrine Tumore zu behandeln.
Bert, Tillmann, Simon, B. (PD Dr. med)
core   +1 more source

Preemptive iodide treatment in the event of a nuclear disaster: The prepper's guide to the galaxy

Experimental Physiology, Volume 110, Issue 12, Page 1771-1776, December 1, 2025.
Per Karkov Cramon, Søren Holm, Ronan M. G. Berg   +2 more
wiley   +1 more source

Further studies on the iodine concentration of conventional, organic and UHT semi-skimmed milk at retail in the UK [PDF]

, 2010
Milk is the largest source of iodine in UK diets and earlier studies showed organic summer and winter milk to be significantly lower in iodine than conventional milk. One study also showed UHT milk to have lower iodine concentration.
Melissa C. Stevenson, Chris Drake, D. Ian Givens, Andersson, Arrizabalaga, Bath, Bath, Bath, Bivolarska, Crnkić, De La Vieja, Fecher, Flachowsky, Food Standards Agency, Grau, Hynes, Miller, Payling, Phillips, Rey-Crespo, Średnicka-Tober, Trøan, Vanderpump, WHO   +23 more
core   +1 more source

Homology of pendrin sodium-iodide symporter and apical iodide transporter

Frontiers in Bioscience, 2018
We observed local homology between human pendrin and sodium/iodide symporter (NIS), that was absent in the NIS-homologous sodium/monocarboxylate transporter or apical iodide transporter (AIT) which, however, does not transport iodide. Thus, we analyzed the full proteins.
Benvenga, Salvatore, Guarneri, Fabrizio
openaire   +3 more sources

Effect of progestin on thyroid function in female Wistar rats

Frontiers in Endocrinology
IntroductionTo characterize the influence of female-specific hormones on women’s thyroid function, the study investigated the influence of extra progestin from oral contraceptives on inducing thyroid dysfunction.MethodsSixty female Wistar rats were ...
Honglei Xie, Tingting Qian, Tingting Qian, Lanchun Liu, Rong Sun, Wenjing Che, Meng Zhao, Xin Hou, Haowen Pan, Yue Su, Jia Li, Xiaoqiu Dong, Xiaoqiu Dong, Peng Liu, Peng Liu   +14 more
doaj   +1 more source