Results 151 to 160 of about 22,963 (277)

Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes

Molecular Therapy: Oncolytics, 2021
Lipo-oligomers, post-functionalized with ligands to enhance targeting, represent promising new vehicles for the tumor-specific delivery of therapeutic genes such as the sodium iodide symporter (NIS). Due to its iodide trapping activity, NIS is a powerful
Rebekka Spellerberg, Teoman Benli-Hoppe, Carolin Kitzberger, Simone Berger, Kathrin A. Schmohl, Nathalie Schwenk, Hsi-Yu Yen, Christian Zach, Franz Schilling, Wolfgang A. Weber, Roland E. Kälin, Rainer Glass, Peter J. Nelson, Ernst Wagner, Christine Spitzweg   +14 more
doaj  

The uptake of soluble and nanoparticulate imaging isotope in model liver tumours after intra-venous and intra-arterial administration

, 2015
Delivery of chemotherapeutic drugs to tumours by reformulation as nanoparticles has often been proposed as a means of facilitating increased selective uptake, exploiting the increased permeability of the tumour vasculature.
Bell, Jessica L, Bickley, Stephanie A, Debono, Kelly M, Jones, Stephen K, King, David W, Knox, Karen J, Pang, Jian H, Parish, Christopher, Philip, Lee A, Senden, Tim J, Stephens, Ross W, Tanudji, Marcel R, Tapner, Michael J., Winter, Jillean G   +13 more
core   +1 more source

A Bio-inspired Learning and Classification Method for Subcellular Localization of a Plasma Membrane Protein [PDF]

, 2012
International audienceHigh-content cellular imaging is an emerging technology for studying many biological phenomena. statistical analyses on large populations (more than thousands) of cells are required. Hence classifying cells by experts is a very time-
Barlaud, Michel, Bel Haj Ali, Wafa, Crescence, Lydie, Darcourt, Jacques, Ferhat, Oumelkheir, Giampaglia, Dario, Piro, Paolo, Pourcher, Thierry   +7 more
core   +1 more source

Cloning of a functional promoter of the human sodium/iodide-symporter gene [PDF]

, 1998
Michaël Behr, Thomas Schmitt, Celia R. Espinoza, U. Loos   +3 more
openalex   +1 more source

Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell–Mediated Sodium Iodide Symporter (NIS) Gene 131I Therapy

Clinical Cancer Research, 2019
Purpose: The innate tumor homing potential of mesenchymal stem cells (MSCs) has been used for a targeted delivery of the theranostic sodium iodide symporter (NIS) transgene into solid tumors. We have previously shown that external beam radiotherapy (EBRT)
C. Schug, Carolin Kitzberger, W. Sievert, Rebekka Spellerberg, Mariella Tutter, Kathrin A Schmohl, B. Eberlein, T. Biedermann, K. Steiger, C. Zach, M. Schwaiger, G. Multhoff, E. Wagner, P. Nelson, C. Spitzweg   +14 more
semanticscholar   +1 more source

Survivin-Sodium Iodide Symporter Reporter as a Non-Invasive Diagnostic Marker to Differentiate Uterine Leiomyosarcoma from Leiomyoma. [PDF]

Cells, 2023
Garcia N, Ulin M, Yang Q, Ali M, Bosland MC, Zeng W, Chen L, Al-Hendy A.   +7 more
europepmc   +1 more source

Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression [PDF]

, 2000
Takahiko Kogai, Francesco Curcio, Shigeyo Hyman, Cornford Em, GA Brent, JM Hershman   +5 more
openalex   +1 more source

Прогностическое значение экспрессии натрий-йодного симпортера для высокодифференцированного рака щитовидной железы

Клиническая и экспериментальная тиреоидология, 2015
The clue function of thyroid follicular cells is iodide (I) uptake and thyroid hormones production. NIS mediates the active transport of I into the thyroid follicular cells.
Dmitriy Yur'evich Semenov, Marina Evgen'evna Boriskova, Ul'yana Valentinovna Farafonova, Roman Viktorovich Grozov, Polina Aleksandrovna Pankova, Ekaterina Nikolaevna Smolina   +5 more
doaj   +1 more source

Failure of Membrane Targeting Causes the Functional Defect of Two Mutant Sodium Iodide Symporters¹ [PDF]

, 2000
Joachim Pohlenz, Laurence Duprez, Roy E. Weiss, Gilbert Vassart, Samuel Refetoff, Sabine Costagliola   +5 more
openalex   +1 more source

High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library.

Environmental Science and Technology, 2018
Thyroid uptake of iodide via the sodium-iodide symporter (NIS) is the first step in the biosynthesis of thyroid hormones that are critical for health and development in humans and wildlife.
Jun Wang, D. Hallinger, A. Murr, A. Buckalew, S. Simmons, S. Laws, T. Stoker   +6 more
semanticscholar   +1 more source