Results 221 to 230 of about 10,644 (242)

Gene therapy with sodium/iodide symporter in hepatocarcinoma

Experimental and Clinical Endocrinology & Diabetes, 2001
The ability of thyroid cells to accumulate iodide is a prerequisite for successful radioiodide therapy of benign thyroid diseases and differentiated thyroid carcinoma. The transport of iodide across the cell membrane is mediated by the sodium iodide symporter (hNIS). Employing a bicistronic retroviral vector for the transfer of the hNIS coding sequence
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Expression of the Sodium/Iodide Symporter in Human Prostate Adenocarcinoma

Urology, 2010
To analyze expression of the sodium/iodide symporter (NIS) in tissue specimen from a large series of patients with prostate adenocarcinoma. Few data are available on the NIS expression in prostate tumor tissues.NIS protein expression was examined by immunohistochemistry in 78 tumor tissue specimen and their non-neoplastic counterparts.
M. Navarra, MICALI, Salvatore, SM lepore, AM Cesinaro, M. Celano, MC Sighinolfi, C. De Gaetani, S. Filetti, BIANCHI, Giampaolo, D. Russo   +9 more
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Sodium Iodide Symporter and Pendrin Expression in Human Thyroid Tissues

Thyroid, 2001
Thyroid cells synthesize thyroid hormones through a multistep process during which iodide is transported through the basolateral and the apical membranes of thyrocytes. Two genes that participate in these transports and the corresponding proteins, namely sodium iodide symporter (NIS) and pendrin, the product of the Pendred syndrome gene, have recently ...
MIAN, CATERINA, LACROIX L, ALZIEU L, NOCERA M, TALBOT M, BIDART JM, SCHLUMBERGER M, CAILLOU B.   +7 more
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Molecular nuclear medicine using sodium/iodide symporter

International Congress Series, 2004
Abstract Iodide uptake occurs across the membrane of thyroid cells via an active transporter, sodium/iodide symporter (NIS). Decreased NIS expression levels account for the reduced iodide uptake in thyroid carcinomas. We found that thyroid cancer patients with positive immunostaining for NIS responded to I-131 therapy better than did the patients ...
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Sodium Iodide Symporter in the Fight Against Thyroid Cancer

Future Oncology, 2013
n radioiodide n signal transduction inhibitor n sodium iodide symporter n thyroid cancer More than 60 years of experience of radioiodide therapy has indicated its usefulness for the treatment of differentiated thyroid cancer. This therapy utilizes the differentiated function of thyroid cells, namely iodide uptake for thyroid hormone synthesis.
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Sodium Iodide Symporter in Thyroid Carcinoma

2012
Thyroid iodide uptake is essential for the clinical application of radioiodine in patients with well-differentiated thyroid carcinoma. Iodide uptake occurs across the plasma membranes of thyroid follicular cells and cancer cells via an active transporter process mediated by sodium iodide symporter (NIS).
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Visualisation of sodium-iodide symporter

European Journal of Nuclear Medicine and Molecular Imaging, 2005
Montserrat, Estorch, Luis, de Andres, Valle, Camacho, Jordi, Fuertes, Ato, Rodriguez, Albert, Flotats, Ignasi, Carrio   +6 more
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Clinical Relevance of the Thyroid Sodium/Iodide Symporter

2003
The first step in the formation of thyroid hormones (TH) involves the active accumulation of iodide from the extracellular fluid across the basolateral membrane and into the thyroid follicular cell. The protein responsible for this was previously described as the iodide trap or iodide pump.
Peter H. K. Eng, Su-Chin Ho
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The sodium iodide symporter and thyroid disease

Clinical Endocrinology, 2002
Peter P A, Smyth, Roisin M, Dwyer
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Sodium Iodide Symporter

2004
Armin E. Heufelder, Werner Joba
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