Results 231 to 240 of about 22,963 (277)

Genetic Defects in Thyroid Hormone Supply. [PDF]

, 2014
FENZI, GIANFRANCO, MACCHIA, PAOLO EMIDIO, NETTORE, IMMACOLATA CRISTINA   +2 more
core  

Preclinical efficacy of the oncolytic measles virus expressing the sodium iodide symporter in iodine non-avid anaplastic thyroid cancer: a novel therapeutic agent allowing noninvasive imaging and radioiodine therapy

, 2012
Honey V. Reddi, Pranathi Madde, Samantha J. McDonough, María A. Trujillo, John C. Morris, Rae Myers, Kah-Whye Peng, Stephen J. Russell, Bryan McIver, Norman L. Eberhardt   +9 more
openalex   +1 more source

Pro-tumorigenic non-pump function of sodium iodide symporter: A reimagined Trojan horse? [PDF]

Oncotarget, 2019
Feng F, Yehia L, Eng C.
europepmc   +1 more source

The Effect of Tanespimycin (17-AAG) on Radioiodine Accumulation in Sodium-Iodide Symporter Expressing Cells

, 2012
Kyoung Hyun Yu, Hyewon Youn, Myung Geun Song, Dong Soo Lee, June-Key Chung   +4 more
openalex   +2 more sources

Prognostic Significance of Sodium Iodide Symporter and Deiodinase Enzymes mRNA Expression in Gastric Cancer.

Int J Appl Basic Med Res, 2020
Mishra A, Shrivastava A.
europepmc   +1 more source

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Curcumin enhances the membrane trafficking of the sodium iodide symporter and augments radioiodine uptake in dedifferentiated thyroid cancer cells via suppression of the PI3K-AKT signaling pathway.

Food & Function, 2021
Radioactive iodine (RAI) is commonly used to treat differentiated thyroid cancer (DTC). A major challenge is the dedifferentiation of DTC with the loss of radioiodine uptake.
Li Zhang, Shichen Xu, Xian Cheng, Jing Wu, Xiaowen Wang, Liying Wu, Huixin Yu, Jiandong Bao   +7 more
semanticscholar   +1 more source

The PDZ protein SCRIB regulates sodium/iodide symporter (NIS) expression at the basolateral plasma membrane

The FASEB Journal, 2021
The sodium/iodide symporter (NIS) expresses at the basolateral plasma membrane of the thyroid follicular cell and mediates iodide accumulation required for normal thyroid hormonogenesis.
Mariano Martín, L. Salleron, Victoria Peyret, R. C. Geysels, E. Darrouzet, S. Lindenthal, Carlos Eduardo Bernal Barquero, A. Masini-Repiso, T. Pourcher, J. Nicola   +9 more
semanticscholar   +1 more source

An intramolecular ionic interaction linking defective sodium/iodide symporter transport to the plasma membrane and dyshormonogenic congenital hypothyroidism.

Thyroid, 2021
BACKGROUND The sodium/iodide symporter (NIS) mediates active iodide accumulation in the thyroid follicular cell. Autosomal recessive iodide transport defect (ITD)-causing loss-of-function NIS variants lead to dyshormonogenic congenital hypothyroidism due
Carlos Eduardo Bernal Barquero, Mariano Martín, R. C. Geysels, Victoria Peyret, P. Papendieck, A. Masini-Repiso, A. Chiesa, J. Nicola   +7 more
semanticscholar   +1 more source

Impact of the mutational landscape of the sodium/iodide symporter in congenital hypothyroidism.

Thyroid, 2021
BACKGROUND Iodide transport defect (ITD) is an uncommon cause of dyshormonogenic congenital hypothyroidism due to homozygous or compound heterozygous pathogenic variants in the SLC5A5 gene, which encodes the sodium/iodide symporter (NIS), causing ...
Mariano Martín, J. Nicola
semanticscholar   +1 more source