Results 61 to 70 of about 5,274 (210)

Suppression of Hippocampal Neurogenesis and Oligodendrocyte Maturation Similar to Developmental Hypothyroidism by Maternal Exposure of Rats to Ammonium Perchlorate, a Gunpowder Raw Material and Known Environmental Contaminant

Environmental Toxicology, Volume 40, Issue 1, Page 30-53, January 2025.
ABSTRACT The environmental contaminant perchlorate raises concern for hypothyroidism‐related brain disorders in children. This study investigated the effects of developmental perchlorate exposure on hippocampal neurogenesis and oligodendrocyte (OL) development.
Yuri Sakamaki, Momoka Shobudani, Ryota Ojiro, Shunsuke Ozawa, Qian Tang, Xinyu Zou, Yuri Ebizuka, Ayumi Karasawa, Gye‐Hyeong Woo, Toshinori Yoshida, Makoto Shibutani   +10 more
wiley   +1 more source

An approach to membrane computing under inexactitude [PDF]

arXiv, 2004
In this paper we introduce a fuzzy version of symport/antiport membrane systems. Our fuzzy membrane systems handle possibly inexact copies of reactives and their rules are endowed with threshold functions that determine whether a rule can be applied or not to a given set of objects, depending of the degree of accuracy of these objects to the reactives ...
arxiv  

Risks to human and animal health from the presence of bromide in food and feed

EFSA Journal, Volume 23, Issue 1, January 2025.
Abstract The European Commission mandated EFSA to assess the toxicity of bromide, the existing maximum residue levels (MRLs), and possible transfer from feed into food of animal origin. The critical effects of bromide in experimental animals are on the thyroid and central nervous system.
EFSA Scientific Committee, Susanne Hougaard Bennekou, Ana Allende, Angela Bearth, Josep Casacuberta, Laurence Castle, Tamara Coja, Amélie Crépet, Thorhallur Halldorsson, Laurentius (Ron) Hoogenboom, Helle Knutsen, Konstantinos Koutsoumanis, Claude Lambré, Søren Nielsen, Dominique Turck, Antonio Vicent Civera, Roberto Villa, Holger Zorn, Vasileios Bampidis, Jacqueline Castenmiller, Marie‐Christine Chagnon, Bruce Cottrill, Keyvin Darney, Jürgen Gropp, Secundino Lopez Puente, Martin Rose, Marco Vinceti, Maria Bastaki, Petra Gergelová, Luna Greco, Matteo Lorenzo Innocenti, Judit Janossy, Anna Lanzoni, Andrea Terron, Diane Benford   +34 more
wiley   +1 more source

Sodium Iodide Symporter and Phosphatase and Tensin Homolog Deleted on Chromosome Ten Expression in Cholangiocarcinoma Analysis with Clinicopathological Parameters

Gut and Liver, 2012
Background/AimsThis study was performed to investigate the correlation of sodium iodide symporter (NIS) expression with the functionality and loss of phosphatase and tensin homolog deleted on chromosome ten (PTEN) expression in human cholangiocarcinoma ...
doaj   +1 more source

Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

BMC Cancer, 2002
Background Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of thyroid cancer.
Schlumberger Martin, Russo Diego, Bidart Jean-Michel, Arturi Franco, Brunetti Antonio, Chiefari Eusebio, Filetti Sebastiano   +6 more
doaj   +1 more source

CRISPR/Cas9‐mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell‐derived cardiomyocytes

Stem Cells Translational Medicine, 2020
Techniques that enable longitudinal tracking of cell fate after myocardial delivery are imperative for optimizing the efficacy of cell‐based cardiac therapies.
John W. Ostrominski, Ravi Chandra Yada, Noriko Sato, Michael Klein, Ksenia Blinova, Dakshesh Patel, Racquel Valadez, Maryknoll Palisoc, Stefania Pittaluga, Kah‐Whye Peng, Hong San, Yongshun Lin, Falguni Basuli, Xiang Zhang, Rolf E. Swenson, Mark Haigney, Peter L. Choyke, Jizhong Zou, Manfred Boehm, So Gun Hong, Cynthia E. Dunbar   +20 more
doaj   +1 more source

Quantum Theory on Glucose Transport Across Membrane [PDF]

arXiv, 2014
After a brief review of the protein folding quantum theory and a short discussion on its experimental evidences the mechanism of glucose transport across membrane is studied from the point of quantum conformational transition. The structural variations among four kinds of conformations of the human glucose transporter GLUT1 (ligand free occluded ...
arxiv  

Preemptive iodide treatment in the event of a nuclear disaster: The prepper's guide to the galaxy

Experimental Physiology, EarlyView.
Per Karkov Cramon, Søren Holm, Ronan M. G. Berg   +2 more
wiley   +1 more source

Disruption of the creb3l1 gene causes defects in caudal fin regeneration and patterning in zebrafish Danio rerio

Developmental Dynamics, Volume 253, Issue 12, Page 1106-1129, December 2024.
Abstract Background The gene cAMP‐Responsive Element Binding protein 3‐like‐1 (CREB3L1) has been implicated in bone development in mice, with CREB3L1 knock‐out mice exhibiting fragile bones, and in humans, with CREB3L1 mutations linked to osteogenesis imperfecta.
Peyton E. VanWinkle, Eunjoo Lee, Bridge Wynn, Tomasz J. Nawara, Holly Thomas, John Parant, Cecilia Alvarez, Rosa Serra, Elizabeth Sztul   +8 more
wiley   +1 more source

Radioactive Iodine Therapy and Glucose Tolerance

Cell Journal, 2017
Radioactive iodine therapy is commonly used as an adjuvant therapy in follicular and papillary thyroid carcinoma (PTC) and in the treatment of Graves’ disease (GD).
Roghaieh Samadi, Asghar Ghasemi, Babak Shafiei, Fereidoun Azizi   +3 more
doaj   +1 more source