Results 81 to 90 of about 10,644 (242)

Comparison of and as Reporter Genes for Noninvasive Imaging of Bone Mesenchymal Stem Cells Transplanted into Infarcted Rat Myocardium

Molecular Imaging, 2011
The purpose of this study was to investigate and compare the feasibility of rat sodium iodide symporter ( rNIS ) and human sodium iodide symporter ( hNIS ) as reporter genes for noninvasive monitoring of rat bone marrow mesenchymal stem cells (rBMSCs ...
Shuo Hu, Wei Cao, Xiaoli Lan, Yong He, Juntao Lang, Congjiao Li, Jia Hu, Rei An, Zairong Gao, Yongxue Zhang   +9 more
doaj   +1 more source

Study on the Iodine 125 Uptake of H460 Lung Cancer Cell Line by Co-transfection with the Human Sodium/Iodide Symporter and the Human Thyroperoxidase [PDF]

, 2010
Background and objective Lung cancer harms people’s health or even lives severely. Especially, the therapy of non-small cell lung cancer (NSCLC) has not been obviously improved for many years.
Jian TAN, Lei LONG, Wei LI
core  

Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation [PDF]

, 2019
Background: The existence of differentiated thyroid cells is critical to respond radioactive iodide treatment strategy in thyroid cancer, and loss of the differentiated phenotype is a trademark of iodide-refractive thyroid disease.
���������
core   +1 more source

Thyroid Cancer: Pathogenesis, Clinicopathology, Diagnosis, and Management

MedComm, Volume 6, Issue 11, November 2025.
Thyroid cancer risk is influenced by both genetic and modifiable factors, including mutations, radiation exposure, lifestyle, and pre‐existing benign conditions. Diagnosis involves physical exams, ultrasound, scintigraphy, laboratory tests, and fine‐needle aspiration biopsy (FNAB).
Yu‐Dong Li, Qing‐Yao Ye, Yan‐Xing Chen, Xia‐Rong Hu   +3 more
wiley   +1 more source

Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

BMC Cancer, 2002
Background Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of thyroid cancer.
Schlumberger Martin, Russo Diego, Bidart Jean-Michel, Arturi Franco, Brunetti Antonio, Chiefari Eusebio, Filetti Sebastiano   +6 more
doaj   +1 more source

Evaluation of the diphenyl herbicide, oxyfluorfen, for effects on thyroid hormones in the juvenile rat

Current Research in Toxicology
Recently, oxyfluorfen, a pre- and post-emergent diphenyl ether herbicide, was identified in our laboratory as an inhibitor of iodide uptake by the sodium iodide symporter (NIS), the first key step in the synthesis of thyroid hormones (THs).
T.E. Stoker, G.D. DeVane, A.R. Buckalew, J.R. Bailey, J.L. Ford, A.S. Murr   +5 more
doaj   +1 more source

Molecular In Vivo Imaging Using a Noninvasive Cardiac-Specific MLC-2v Promoter Driven Dual-Gene Recombinant Lentivirus Monitoring System. [PDF]

PLoS ONE, 2015
Our study aimed to demonstrate the feasibility of using the sodium/iodide symporter (NIS) to monitor vascular endothelial growth factor (VEGF165) expression in vivo.We constructed a recombinant lentivirus plasmid with the MLC-2v promoter driving the ...
Miao Zhang, Lihua Wang, Rui Guo, Sheng Liang, Xufeng Jiang, Min Zhang, Biao Li   +6 more
doaj   +1 more source

Relationship between PI3K Mutation and Sodium-Iodide Symporter in Anaplastic Thyroid Carcinoma [PDF]

, 2015
The sodium-iodide symporter is a transmembrane protein that has important role in radio-iodide therapy in various cancers such as anaplastic thyroid carcinoma.
Bozorg-Ghalati, Farzaneh, Hedayati, Mehdi   +1 more
core  

Peritoneal Immunosurgery: Immunotherapy Augmented Surgery for the Treatment of Peritoneal Cancers

Journal of Surgical Oncology, Volume 132, Issue 5, Page 789-809, October 2025.
ABSTRACT Peritoneal malignancy often indicates disruptions in multiple physiological systems resulting from widespread cancer. The heterogenous origin and dynamic nature of peritoneal cancer make it difficult to treat with standard approaches that fit into guidelines.
Ada I. Ozcan, Arianexys Aquino López, Mary K. McKenna, Malcolm K. Brenner, Alastair M. Thompson   +4 more
wiley   +1 more source

CRISPR/Cas9‐mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell‐derived cardiomyocytes

Stem Cells Translational Medicine, 2020
Techniques that enable longitudinal tracking of cell fate after myocardial delivery are imperative for optimizing the efficacy of cell‐based cardiac therapies.
John W. Ostrominski, Ravi Chandra Yada, Noriko Sato, Michael Klein, Ksenia Blinova, Dakshesh Patel, Racquel Valadez, Maryknoll Palisoc, Stefania Pittaluga, Kah‐Whye Peng, Hong San, Yongshun Lin, Falguni Basuli, Xiang Zhang, Rolf E. Swenson, Mark Haigney, Peter L. Choyke, Jizhong Zou, Manfred Boehm, So Gun Hong, Cynthia E. Dunbar   +20 more
doaj   +1 more source