Results 81 to 90 of about 5,274 (210)

Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis

open access: yesInternational Journal of Endocrinology, 2014
Aim. The aim of the study was to compare the expression of sodium iodide symporter (NIS), thyroglobulin (Tg), tumor necrosis factor-α (TNFα), and interleukin-1β genes in patients with Hashimoto’s thyroiditis (HT) and healthy individuals.
Anna Popławska-Kita   +11 more
doaj   +1 more source

Sodium Iodide Symporter PET and BLI Noninvasively Reveal Mesoangioblast Survival in Dystrophic Mice

open access: yesStem Cell Reports, 2015
Muscular dystrophies are a heterogeneous group of myopathies, characterized by muscle weakness and degeneration, without curative treatment. Mesoangioblasts (MABs) have been proposed as a potential regenerative therapy.
Bryan Holvoet   +10 more
doaj   +1 more source

High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition

open access: yesEnvironment International, 2019
In support of the Endocrine Disruptor Screening Program (EDSP), the U.S.EPA's Office of Research and Development (ORD) is developing high-throughput screening (HTS) approaches to identify chemicals that alter target sites in the thyroid hormone (TH ...
Jun Wang   +7 more
doaj  

Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes

open access: yesMolecular Therapy: Oncolytics, 2021
Lipo-oligomers, post-functionalized with ligands to enhance targeting, represent promising new vehicles for the tumor-specific delivery of therapeutic genes such as the sodium iodide symporter (NIS). Due to its iodide trapping activity, NIS is a powerful
Rebekka Spellerberg   +14 more
doaj  

Homology of pendrin sodium-iodide symporter and apical iodide transporter

open access: yesFrontiers in Bioscience, 2018
We observed local homology between human pendrin and sodium/iodide symporter (NIS), that was absent in the NIS-homologous sodium/monocarboxylate transporter or apical iodide transporter (AIT) which, however, does not transport iodide. Thus, we analyzed the full proteins.
Benvenga, Salvatore, Guarneri, Fabrizio
openaire   +4 more sources

Advances in molecular mechanisms of iodine-131 therapy resistance in thyroid carcinoma

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban
Thyroid cancer is the most common malignant tumor of the endocrine system, with differentiated thyroid carcinoma (DTC) accounting for over 90%. Most DTC patients have a good prognosis after systematic treatment, but a few develop dedifferentiation of ...
LIU Shiqi, WANG Hui, FENG Fang
doaj   +1 more source

Прогностическое значение экспрессии натрий-йодного симпортера для высокодифференцированного рака щитовидной железы

open access: yesКлиническая и экспериментальная тиреоидология, 2015
The clue function of thyroid follicular cells is iodide (I) uptake and thyroid hormones production. NIS mediates the active transport of I into the thyroid follicular cells.
Dmitriy Yur'evich Semenov   +5 more
doaj   +1 more source

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